Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 1/20 | 0.39 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.37 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.37 |
| ▸ | KCNQ4 | P56696 | 1/20 | 0.37 |
| ▸ | KCNQ5 | Q9NR82 | 1/20 | 0.37 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.36 |
| ▸ | MGLL | Q99685 | 1/20 | 0.36 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.35 |
| ▸ | CSF1R | P07333 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.34 |
| ▸ | PREP | P48147 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28524216 | 0.82 | GAA (0.46) | KDM4EALDH1A1LMNAHSD17B10MAPT | |
| SCHEMBL8209503 | 0.81 | KLKB1 (0.45) | PPARDGRM2KDM4EALDH1A1KCNH2 | |
| SCHEMBL28517068 | 0.81 | PPARD (0.39) | PPARDKCNQ3KCNQ2KCNQ4KCNQ5 | |
| SCHEMBL28908750 | 0.80 | GCGR (0.40) | PPARDMRGPRX4KCNH2GPR119 | |
| SCHEMBL21503682 | 0.80 | LOXL2 (0.40) | PPARDKCNH2LMNAGRIN1GRIN2B | |
| Hydrochloric Acid SCHEMBL21491894 | 0.79 | LMNA (0.41) | PPARDKCNH2LMNAGRIN1GRIN2B | |
| Hydrochloric Acid SCHEMBL30744436 | 0.79 | LMNA (0.41) | PPARDKCNH2LMNAGRIN1GRIN2B | |
| SCHEMBL28524436 | 0.78 | GRM2 (0.31) | GRM2LMNAKLKB1 | |
| SCHEMBL21492571 | 0.78 | GRIN1 (0.38) | PPARDKDM4EALDH1A1KCNH2CSF1R | |
| SCHEMBL21491889 | 0.78 | KLKB1 (0.44) | PPARDNAMPTGLSKLKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112218865-B | Pteridinone compounds and uses thereof | 沃泰克斯药物股份有限公司 | 2024-03-12 | — | — | CN | disclosed |
| CN-112218865-A | Pteridinone compounds and uses thereof | 沃泰克斯药物股份有限公司 | 2021-01-12 | — | — | CN | disclosed |