Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.41 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.41 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28514507 | 0.85 | TAAR1 (0.50) | TAAR1SLC6A3KCNH2 | |
| SCHEMBL28510956 | 0.85 | ALDH1A1 (0.41) | TLR9TLR8TLR7TAAR1 | |
| SCHEMBL28517855 | 0.76 | — | — | |
| SCHEMBL27700096 | 0.70 | PRKACA (0.42) | — | |
| SCHEMBL4544194 | 0.68 | PRKDC (0.47) | TAAR1KCNH2 | |
| SCHEMBL28517851 | 0.67 | RAF1 (0.51) | — | |
| SCHEMBL4410817 | 0.67 | DRD2 (0.46) | TLR9TLR8TLR7TAAR1SLC6A3 | |
| SCHEMBL28834106 | 0.67 | SLC6A3 (0.44) | TAAR1SLC6A3KCNH2 | |
| SCHEMBL27932853 | 0.66 | DRD2 (0.42) | — | |
| SCHEMBL3404764 | 0.66 | DRD2 (0.53) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107721937-B | Preparation method and application of compound containing pyrimidone skeleton | 沈阳药科大学 | 2021-02-05 | — | — | CN | disclosed |