Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR3 | O14843 | 1/20 | 0.44 |
| ▸ | LCK | P06239 | 1/20 | 0.44 |
| ▸ | FYN | P06241 | 1/20 | 0.44 |
| ▸ | ELANE | P08246 | 10/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | PRKCA | P17252 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1141547 | 0.90 | ELANE (0.40) | ELANEALDH1A1TSHRPRKCAPOLB | |
| SCHEMBL31361800 | 0.87 | ELANE (0.39) | ELANEALDH1A1TSHRPRKCAPOLB | |
| SCHEMBL247159 | 0.85 | ALDH1A1 (0.35) | ELANEALDH1A1TSHRPRKCA | |
| SCHEMBL28850623 | 0.78 | ELANE (0.37) | ELANEALDH1A1TSHRPRKCAPOLB | |
| SCHEMBL30972534 | 0.78 | ELANE (0.37) | ELANEALDH1A1TSHRPRKCAPOLB | |
| SCHEMBL6821171 | 0.75 | — | — | |
| SCHEMBL17706792 | 0.75 | — | — | |
| SCHEMBL7563019 | 0.75 | DGAT1 (0.36) | ELANEALDH1A1TSHRPRKCA | |
| SCHEMBL6921707 | 0.73 | ALDH1A1 (0.35) | FFAR3LCKFYNELANEALDH1A1 | |
| SCHEMBL6821168 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112080184-A | Anti-whitening primer and preparation method thereof | 英济股份有限公司 | 2020-12-15 | — | — | CN | claimed |