SCHEMBL7563019

SCHEMBL7563019

COC(=O)OOC(=O)C(C)(C)C

nearest known ligand 0.36

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
DGAT1 O75907 1/20 0.36
PRKCA P17252 1/20 0.33
ELANE P08246 3/20 0.32
ALDH1A1 P00352 1/20 0.32
TSHR P16473 1/20 0.31
HSD17B10 Q99714 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1141547 0.83 ELANE (0.40) DGAT1PRKCAELANEALDH1A1TSHR
SCHEMBL31361800 0.80 ELANE (0.39) DGAT1PRKCAELANEALDH1A1TSHR
SCHEMBL804118 0.80 ALDH1A1 (0.47) ALDH1A1TSHRHSD17B10
SCHEMBL8664776 0.76 ALDH1A1 (0.40) DGAT1PRKCAELANEALDH1A1
SCHEMBL6821171 0.75
Acetic Acid SCHEMBL28518327 0.75 FFAR3 (0.44) PRKCAELANEALDH1A1TSHR
SCHEMBL4328011 0.74
SCHEMBL15139 0.74
SCHEMBL247159 0.72 ALDH1A1 (0.35) PRKCAELANEALDH1A1TSHR
SCHEMBL247157 0.72 PRKCA (0.36) PRKCAELANE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119799782-A Modification regulation gene editing method based on sgRNA 武汉大学中南医院 2025-04-11 CN claimed
EP-1077981-B1 NOVEL CEPHALOSPORIN COMPOUNDS, PROCESSES FOR PREPARATION THEREOF AND ANTIMICROBIAL COMPOSITIONS CONTAINING THE SAME LG CHEMICAL LTD (KR) 2002-08-07 EP claimed
US-12509466-B2 Methods and compounds for treating paramyxoviridae virus infections GILEAD SCIENCES, INC. (US) 2025-12-30 US disclosed
US-20250321207-A1 Chromatography NOVA PRIMARY MANUFACTURING LTD (GB) 2025-10-16 US disclosed
CN-119451666-A Lipid nanoparticles for gene editing systems 奥泽生物疗法公司 2025-02-14 CN disclosed
CN-119110732-A Gene editing for improving joint function 奥泽生物疗法公司 2024-12-10 CN disclosed
CN-119053696-A Transmembrane receptor gene editing 奥泽生物疗法公司 2024-11-29 CN disclosed
EP-3932931-B1 A NEBULIZER COMPRISING A PHARMACEUTICAL COMPOSITION COMPRISING 2'-SUBSTITUTED CARBA-NUCLEOSIDE ANALOGS FOR ANTIVIRAL TREATMENT GILEAD SCIENCES INC (US) 2024-11-20 EP disclosed
EP-3519409-B1 BENZOTHIAZOL-6-YL ACETIC ACID DERIVATIVES AND THEIR USE FOR TREATING HIV INFECTION GILEAD SCIENCES INC (US) 2024-09-18 EP disclosed
US-12037340-B2 Pentacyclic derivatives as Zika virus inhibitors GILEAD SCIENCES, INC. (US) 2024-07-16 US disclosed
EP-4341266-A1 PENTACYCLIC DERIVATIVES AS ZIKA VIRUS INHIBITORS GILEAD SCIENCES, INC. (US) 2024-03-27 EP disclosed
EP-3897688-B9 USE OF SAP FOR THE TREATMENT OF EUROTIOMYCETES FUNGI INFECTIONS HUMANITAS MIRASOLE SPA (IT) 2023-10-04 EP disclosed
EP-3897688-B1 USE OF SAP FOR THE TREATMENT OF EUROTIOMYCETES FUNGI INFECTIONS HUMANITAS MIRASOLE SPA (IT) 2023-06-07 EP disclosed
US-20230012449-A1 COMPOUNDS FOR THE TREATMENT OF HIV GILEAD SCIENCES, INC. 2023-01-12 US disclosed
US-20220411434-A1 PENTACYCLIC DERIVATIVES AS ZIKA VIRUS INHIBITORS GILEAD SCIENCES, INC. 2022-12-29 US disclosed
WO-2022246109-A1 PENTACYCLIC DERIVATIVES AS ZIKA VIRUS INHIBITORS GILEAD SCIENCES, INC. (US) 2022-11-24 WO disclosed
US-11492353-B2 Methods and compounds for treating Paramyxoviridae virus infections GILEAD SCIENCES, INC. (US) 2022-11-08 US disclosed
EP-2937350-B9 1' -substituted carba-nucleoside analogs for antiviral treatment GILEAD SCIENCES INC (US) 2022-08-17 EP disclosed
US-20220227776-A1 PRODRUGS OF 1'-SUBSTITUTED CARBA-NUCLEOSIDE ANALOGUES FOR ANTIVIRAL TREATMENT Copycat Sciences Inc. (US) 2022-07-21 US disclosed
WO-2022098371-A1 PRODRUGS OF 1'-SUBSTITUTED CARBA-NUCLEOSIDE ANALOGUES FOR ANTIVIRAL TREATMENT YAN MATTHEW (US) 2022-05-12 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220411434-A1 PENTACYCLIC DERIVATIVES AS ZIKA VIRUS INHIBITORS ZC3HAV1, ZC3HAV1L, EIF2AK2 DGAT1 885/4885PRKCA 3745/4885ELANE 2889/4885
US-11492353-B2 Methods and compounds for treating Paramyxoviridae virus infections PNP, RPIA, HPRT1 DGAT1 3753/4885PRKCA 1530/4885ELANE 1217/4885
US-12509466-B2 Methods and compounds for treating paramyxoviridae virus infections MTAP, PNP, NSUN2 DGAT1 4695/4885PRKCA 666/4885ELANE 4050/4885
US-20220227776-A1 PRODRUGS OF 1'-SUBSTITUTED CARBA-NUCLEOSIDE ANALOGUES FOR ANTIVIRAL TREATMENT ACE2, ACE, PNP DGAT1 620/4885PRKCA 1074/4885ELANE 1495/4885
US-12037340-B2 Pentacyclic derivatives as Zika virus inhibitors ZC3HAV1, ZC3HAV1L, GDI1 DGAT1 868/4885PRKCA 3776/4885ELANE 2797/4885
US-20230012449-A1 COMPOUNDS FOR THE TREATMENT OF HIV CCR5, NPC1, FURIN DGAT1 2446/4885PRKCA 3802/4885ELANE 510/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.