Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 5/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | GLS | O94925 | 1/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18275272 | 0.82 | MLYCD (0.50) | SMN1; SMN2NPC1RAB9AMEN1KMT2A | |
| SCHEMBL18275161 | 0.78 | RORC (0.53) | ALDH1A1MAPTNPC1RAB9AMEN1 | |
| SCHEMBL18275292 | 0.77 | KMT2A (0.41) | SMN1; SMN2ALDH1A1MAPTNPC1RAB9A | |
| SCHEMBL18275343 | 0.77 | GLS (0.38) | ALDH1A1MAPTMEN1KMT2AGLS | |
| SCHEMBL28507926 | 0.77 | GAA (0.83) | GAASMN1; SMN2POLBALDH1A1MAPT | |
| SCHEMBL14658652 | 0.76 | NPC1 (0.61) | GAASMN1; SMN2ALDH1A1MAPTNPC1 | |
| SCHEMBL18275168 | 0.76 | RORC (0.41) | SMN1; SMN2ALDH1A1MAPTNPC1RAB9A | |
| SCHEMBL3662503 | 0.75 | GLS (0.45) | GAAPOLBALDH1A1MAPTNPC1 | |
| SCHEMBL18275172 | 0.74 | CYP1A2 (0.40) | POLBALDH1A1MAPTNPC1RAB9A | |
| SCHEMBL31241075 | 0.74 | RAB9A (0.74) | SMN1; SMN2ALDH1A1MAPTNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110218182-B | IDO inhibitors | 南京亘泰医药技术有限公司 | 2021-01-26 | — | — | CN | disclosed |