Acetophenone

Acetophenone

SCHEMBL28519002

CC(=O)c1ccccc1.CCCCOC(=O)O

nearest known ligand 0.56

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 5/20 0.56
HPGD P15428 2/20 0.56
RAB9A P51151 1/20 0.56
TSHR P16473 6/20 0.54
L3MBTL1 Q9Y468 5/20 0.54
TDP1 Q9NUW8 3/20 0.54
ALDH1A1 P00352 5/20 0.49
MAPK1 P28482 3/20 0.49
CYP3A4 P08684 3/20 0.49
TP53 P04637 1/20 0.49
HSD17B10 Q99714 1/20 0.47
CYP1A2 P05177 2/20 0.47
CYP2C19 P33261 2/20 0.47
SMN1; SMN2 Q16637 2/20 0.47
ESR1 P03372 1/20 0.47
CYP2D6 P10635 1/20 0.47
NR1H2 P55055 1/20 0.47
RNASEL Q05823 1/20 0.47
GAA P10253 1/20 0.47
MAOB P27338 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acetophenone SCHEMBL28513709 0.95 TSHR (0.56) LMNAHPGDRAB9ATSHRL3MBTL1
Acetophenone SCHEMBL28262081 0.93 LMNA (0.57) LMNAHPGDRAB9ATSHRTDP1
Acetophenone SCHEMBL28515793 0.93 LMNA (0.57) LMNAHPGDRAB9ATSHRTDP1
Acetophenone SCHEMBL27577933 0.90 ALDH1A1 (0.62) LMNAHPGDRAB9ATSHRL3MBTL1
Acetophenone SCHEMBL28521014 0.89 LMNA (0.65) LMNAHPGDRAB9ATSHRL3MBTL1
Acetophenone SCHEMBL28080259 0.86 L3MBTL1 (0.52) LMNAHPGDRAB9ATSHRL3MBTL1
Dibutyl Phthalate SCHEMBL28131674 0.85 TSHR (0.78) LMNAHPGDRAB9ATSHRL3MBTL1
Benzoyl Peroxide SCHEMBL28876080 0.85 LMNA (0.59) LMNAHPGDRAB9ATSHRL3MBTL1
Propiophenone SCHEMBL28515262 0.85 TSHR (0.53) LMNARAB9ATSHRL3MBTL1TDP1
Acetophenone SCHEMBL28079102 0.85 TSHR (0.56) LMNAHPGDRAB9ATSHRL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109111537-B Catalyst component for olefin polymerization and catalyst thereof 中国石油化工股份有限公司 2021-03-16 CN disclosed
CN-109111539-B Catalyst component for olefin polymerization and catalyst thereof 中国石油化工股份有限公司 2021-02-05 CN disclosed
CN-109111538-B Catalyst component for olefin polymerization and catalyst thereof 中国石油化工股份有限公司 2021-02-05 CN disclosed