Acetophenone

Acetophenone

SCHEMBL28080259

CC(=O)c1ccccc1.CCCCOCCCC

nearest known ligand 0.52

Full drug profile on Sugi Atlas →

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 3/20 0.52
LMNA P02545 3/20 0.51
HPGD P15428 2/20 0.51
RAB9A P51151 1/20 0.51
TSHR P16473 3/20 0.50
GAA P10253 2/20 0.50
RARB P10826 1/20 0.50
RECQL P46063 1/20 0.50
PTGS2 P35354 1/20 0.49
CES2 O00748 2/20 0.49
CES1 P23141 2/20 0.49
MAOB P27338 1/20 0.49
TDP1 Q9NUW8 1/20 0.49
ALDH1A1 P00352 3/20 0.47
SMN1; SMN2 Q16637 2/20 0.47
HTT P42858 1/20 0.47
MAPT P10636 2/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acetophenone SCHEMBL27691350 0.89 LMNA (0.58) L3MBTL1LMNAHPGDRAB9AGAA
Benzophenone SCHEMBL29265024 0.87 ELANE (0.54) L3MBTL1LMNAHPGDTSHRGAA
Benzil SCHEMBL28423464 0.87 CES2 (0.59) L3MBTL1LMNAHPGDTSHRGAA
Benzoic Acid SCHEMBL19411715 0.87 RARB (0.64) LMNATSHRRARBRECQL
Acetophenone SCHEMBL28186100 0.86 CES2 (0.60) LMNAHPGDPTGS2CES2CES1
Acetophenone SCHEMBL27577933 0.86 ALDH1A1 (0.62) L3MBTL1LMNAHPGDRAB9ATSHR
Acetophenone SCHEMBL28519002 0.86 LMNA (0.56) L3MBTL1LMNAHPGDRAB9ATSHR
Acetophenone SCHEMBL15206675 0.84 CES2 (0.61) L3MBTL1LMNAHPGDCES2CES1
Benzoic Acid SCHEMBL12971271 0.82 RARB (0.59) TSHRRARBRECQL
SCHEMBL28385695 0.82 L3MBTL1 (0.53) L3MBTL1LMNAHPGDRAB9ATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105873667-A Composite membrane and method of use thereof 3M创新有限公司 2016-08-17 CN disclosed
CN-105813808-A Conglomerate abrasive particles, abrasive articles including the same, and methods of making the same 3M创新有限公司 2016-07-27 CN disclosed
CN-105722643-A STRUCTURED ABRASIVE ARTICLES AND METHODS OF USING THE SAME 3M创新有限公司 2016-06-29 CN disclosed