Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.35 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31564493 | 0.83 | KDM4E (0.38) | ALDH1A1KMT2AMEN1PTGDR2KDM4E | |
| SCHEMBL6748897 | 0.78 | — | — | |
| SCHEMBL10440459 | 0.76 | MAOA (0.35) | ALDH1A1KMT2AMEN1PTGDR2CYP2A6 | |
| SCHEMBL18995061 | 0.74 | CYP2A6 (0.36) | KMT2AMEN1CYP2A6 | |
| SCHEMBL10424599 | 0.74 | AKR1B1 (0.43) | ALDH1A1KMT2AMEN1PTGDR2KDM4E | |
| SCHEMBL6964424 | 0.74 | — | — | |
| SCHEMBL19222446 | 0.74 | CYP2A6 (0.38) | KMT2AMEN1CYP2A6 | |
| SCHEMBL4416528 | 0.74 | AKR1B1 (0.43) | ALDH1A1KMT2AMEN1PTGDR2KDM4E | |
| SCHEMBL11664361 | 0.73 | KDM5A (0.37) | ALDH1A1KMT2AMEN1PTGDR2KDM4E | |
| SCHEMBL3632023 | 0.72 | ALDH1A1 (0.45) | ALDH1A1KMT2AMEN1PTGDR2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112312927-A | Conjugates for targeting and clearing aggregates | 麦迪穆有限责任公司 | 2021-02-02 | — | — | CN | claimed |
| CN-112312927-A | Conjugates for targeting and clearing aggregates | 麦迪穆有限责任公司 | 2021-02-02 | — | — | CN | disclosed |