Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | GAA | P10253 | 4/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | BLM | P54132 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.41 |
| ▸ | RGS12 | O14924 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | APEX1 | P27695 | 1/20 | 0.41 |
| ▸ | THPO | P40225 | 1/20 | 0.41 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.41 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11538297 | 0.81 | ALOX5 (0.33) | KDM4EMAPTTDP1BLMALDH1A1 | |
| SCHEMBL29274373 | 0.79 | LTB4R (0.43) | KDM4EMAPTTDP1HPGDHSD17B10 | |
| SCHEMBL10424599 | 0.78 | AKR1B1 (0.43) | AKR1B1KDM4EMAPTTDP1POLB | |
| SCHEMBL11241878 | 0.77 | CES1 (0.44) | AKR1B1TDP1ALDH1A1MEN1KMT2A | |
| SCHEMBL7961734 | 0.77 | ADAMTS5 (0.40) | AKR1B1KDM4EMAPTHPGDHSD17B10 | |
| SCHEMBL2778669 | 0.77 | MEN1 (0.43) | AKR1B1KDM4EMAPTGAATDP1 | |
| SCHEMBL11186584 | 0.77 | ALDH1A1 (0.38) | AKR1B1KDM4EMAPTHPGDHSD17B10 | |
| SCHEMBL3632023 | 0.77 | ALDH1A1 (0.45) | AKR1B1KDM4EMAPTHPGDHSD17B10 | |
| SCHEMBL1295399 | 0.77 | ALOX5 (0.51) | KDM4EPOLBALDH1A1MEN1KMT2A | |
| SCHEMBL15380492 | 0.77 | LTB4R (0.47) | AKR1B1KDM4EHPGDHSD17B10POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102648195-B | Novel spiropiperidine compounds | LILLY CO ELI | 2015-01-07 | — | — | CN | disclosed |
| US-20090326004-A1 | MUSCARINIC RECEPTOR ANTAGONISTS | RANBAXY LABORATORIES LIMITED (IN) | 2009-12-31 | — | — | US | disclosed |
| EP-2130830-A1 | Muscarinic receptor antagonists | Ranbaxy Laboratories Limited (IN) | 2009-12-09 | — | — | EP | disclosed |
| US-4508649-A | Process for preparing optically active penems | FARMITALIA CARLO ERBA (IT) | 1985-04-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090326004-A1 | MUSCARINIC RECEPTOR ANTAGONISTS | LTB4R2, LTB4R, LTC4S | AKR1B1 545/4885KDM4E 2709/4885MAPT 3886/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.