Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 7/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | TRPC3 | Q13507 | 2/20 | 0.46 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.42 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | GPR6 | P46095 | 1/20 | 0.41 |
| ▸ | TRPC1 | P48995 | 1/20 | 0.41 |
| ▸ | STIM1 | Q13586 | 1/20 | 0.41 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.41 |
| ▸ | STIM2 | Q9P246 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2852992 | 0.88 | CCR1 (0.53) | CCR1ALDH1A1KDM4EMAPTTRPC3 | |
| SCHEMBL2856202 | 0.84 | CCR1 (0.55) | CCR1ALDH1A1KDM4EMAPTTRPC3 | |
| SCHEMBL1870724 | 0.77 | MAPT (0.56) | CCR1ALDH1A1KDM4EMAPTPOLB | |
| SCHEMBL10365015 | 0.77 | TRPC3 (0.70) | CCR1ALDH1A1KDM4EMAPTTRPC3 | |
| SCHEMBL2852931 | 0.75 | KDM4E (0.57) | CCR1ALDH1A1KDM4EMAPTTRPC3 | |
| SCHEMBL28696410 | 0.75 | ALDH1A1 (0.76) | CCR1ALDH1A1KDM4EMAPTTRPC3 | |
| SCHEMBL2855462 | 0.74 | MAPT (0.54) | CCR1ALDH1A1KDM4EMAPTTRPC3 | |
| SCHEMBL2856793 | 0.74 | KDM4E (0.53) | CCR1ALDH1A1KDM4EMAPTTRPC3 | |
| SCHEMBL5926450 | 0.74 | KDM4E (0.53) | CCR1ALDH1A1KDM4EMAPTPOLB | |
| SCHEMBL2855128 | 0.74 | TRPC3 (0.56) | CCR1ALDH1A1KDM4EMAPTTRPC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | disclosed |