Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 6/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.45 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.45 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27570726 | 0.82 | FFAR1 (0.52) | BCHEMEN1KMT2AFFAR1 | |
| SCHEMBL14965615 | 0.80 | MEP1B (0.50) | BCHEMEN1KMT2ACHRM2POLB | |
| SCHEMBL9416030 | 0.77 | CHRM2 (0.71) | BCHEMEN1KMT2ACHRM2KDM4E | |
| SCHEMBL13999438 | 0.77 | BACE1 (0.50) | BCHECHRM2CD274PDCD1 | |
| SCHEMBL30821452 | 0.76 | BCHE (0.76) | BCHEMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL10011367 | 0.76 | BCHE (0.76) | BCHEMEN1KMT2AKDM4EALDH1A1 | |
| Oxalic Acid SCHEMBL2389436 | 0.75 | PTGS1 (0.44) | BCHEMEN1KMT2AFFAR1POLB | |
| SCHEMBL3684545 | 0.75 | BCHE (0.58) | BCHEMEN1KMT2AFFAR1KDM4E | |
| SCHEMBL21049912 | 0.74 | MMP13 (0.46) | FFAR1KDM4EALDH1A1 | |
| SCHEMBL28038183 | 0.74 | CHRM2 (0.50) | BCHEMEN1KMT2ACHRM2CD274 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112424160-A | Novel P62 ligand compound and composition for preventing, ameliorating or treating protein conformational diseases comprising the same | 普罗泰克株式会社 | 2021-02-26 | — | — | CN | disclosed |