Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEP1B | Q16820 | 1/20 | 0.50 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.48 |
| ▸ | BCHE | P06276 | 4/20 | 0.46 |
| ▸ | USP28 | Q96RU2 | 1/20 | 0.46 |
| ▸ | USP25 | Q9UHP3 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.43 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.43 |
| ▸ | DAO | P14920 | 1/20 | 0.43 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | KCNB1 | Q14721 | 1/20 | 0.42 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14966127 | 0.83 | USP28 (0.62) | CHRM2BCHEUSP28USP25MEN1 | |
| SCHEMBL13766434 | 0.83 | MEP1B (0.48) | MEP1BCHRM2BCHEMEN1KMT2A | |
| SCHEMBL9416030 | 0.81 | CHRM2 (0.71) | CHRM2BCHEMEN1KMT2AKDM4E | |
| SCHEMBL28038183 | 0.81 | CHRM2 (0.50) | CHRM2BCHEUSP28USP25MEN1 | |
| SCHEMBL2002052 | 0.81 | SPHK2 (0.56) | MEP1BMEN1KMT2AROCK2ROCK1 | |
| SCHEMBL28519935 | 0.80 | BCHE (0.50) | CHRM2BCHEMEN1KMT2APOLB | |
| SCHEMBL14965788 | 0.80 | ALDH1A1 (0.54) | CHRM2MEN1KMT2APOLBALDH1A1 | |
| SCHEMBL16421371 | 0.80 | CYP4F2 (0.56) | MEP1BDAOMRGPRX4 | |
| SCHEMBL1776057 | 0.80 | MEP1B (0.54) | MEP1BMEN1KMT2AROCK2DAO | |
| SCHEMBL10859843 | 0.79 | PDCD1 (0.53) | CHRM2MEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013072903-A1 | NITROIMIDAZOXADIAZOCINE COMPOUNDS | ITHEMBA PHARMACEUTICALS (PROPRIETARY) LIMITED (ZA) | 2013-05-23 | — | — | WO | disclosed |
| WO-2013072903-A1 | NITROIMIDAZOXADIAZOCINE COMPOUNDS | ITHEMBA PHARMACEUTICALS (PROPRIETARY) LIMITED (ZA) | 2013-05-23 | — | — | WO | disclosed |