SCHEMBL4153858

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL19553756	0.86	CA1 (0.35)	MAPTLMNA
	SCHEMBL28520119	0.85	MAPT (0.49)	MAPTLMNAKDM4EDUSP3MEN1
	SCHEMBL27734730	0.84	MAPT (0.51)	MAPTLMNAKDM4EDUSP3MEN1
	SCHEMBL5365642	0.84	MAPT (0.51)	MAPTLMNAKDM4EDUSP3MEN1
	Octane SCHEMBL4338103	0.82	CA1 (0.40)	MAPTLPAR1LPAR4LPAR2LPAR3
	SCHEMBL27603184	0.82	MAPT (0.50)	MAPTLMNAKDM4EDUSP3MEN1
	SCHEMBL27496716	0.80	MAPT (0.53)	MAPTLMNAKDM4EDUSP3MEN1
	SCHEMBL27952502	0.78	MAPT (0.56)	MAPTLMNAKDM4EDUSP3MEN1
	SCHEMBL9579019	0.73	LMNA (0.50)	MAPTLMNAKDM4EDUSP3MEN1
	SCHEMBL20504493	0.72	MAPT (0.42)	MAPTLMNAKDM4EDUSP3MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.