Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 4/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | DHFR | P00374 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | APP | P05067 | 1/20 | 0.32 |
| ▸ | GRK6 | P43250 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29987813 | 0.82 | CYP19A1 (0.47) | TAAR1MAOBCYP19A1CYP3A4 | |
| SCHEMBL28528983 | 0.81 | TAAR1 (0.43) | TAAR1GFERMAOBCYP19A1CYP3A4 | |
| SCHEMBL11281993 | 0.74 | TLR8 (0.37) | CYP3A4 | |
| SCHEMBL3364178 | 0.70 | GFER (0.74) | TAAR1GFERMAOBCYP19A1CYP3A4 | |
| SCHEMBL2573719 | 0.68 | MPO (0.44) | TAAR1MAOBPTGS1PTGS2DHFR | |
| SCHEMBL16507870 | 0.68 | TAAR1 (0.54) | TAAR1GFERMAOBCYP19A1PTGS1 | |
| SCHEMBL28190926 | 0.65 | NR3C2 (0.42) | TAAR1GFERCYP19A1PTGS1PTGS2 | |
| SCHEMBL20495035 | 0.64 | CYP19A1 (0.74) | TAAR1GFERMAOBCYP19A1CYP3A4 | |
| SCHEMBL7437052 | 0.63 | TAAR1 (0.68) | TAAR1GFERMAOBPTGS1PTGS2 | |
| SCHEMBL6205019 | 0.61 | TAAR1 (0.48) | TAAR1GFERMAOBMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111792999-B | Dinaphthylamine compounds, and preparation method and application thereof | 五邑大学 | 2022-08-09 | — | — | CN | disclosed |
| CN-111792999-A | Dinaphthylamine compounds, and preparation method and application thereof | 五邑大学 | 2020-10-20 | — | — | CN | disclosed |