Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | CRHBP | P24387 | 1/20 | 0.42 |
| ▸ | MC4R | P32245 | 1/20 | 0.42 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.42 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.41 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | TRPC3 | Q13507 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2851005 | 0.82 | P2RX7 (0.66) | P2RX7KDM4EALDH1A1TRPC3 | |
| SCHEMBL2856265 | 0.81 | MAPT (0.78) | P2RX7MAPTPOLBSMN1; SMN2PTPN1 | |
| SCHEMBL2064195 | 0.80 | MAPT (0.76) | MAPTPOLBSMN1; SMN2PTPN1KDM4E | |
| SCHEMBL2299638 | 0.76 | SMN1; SMN2 (0.57) | MAPTPOLBSMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL2850399 | 0.74 | MAPT (0.74) | MAPTPOLBSMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL2294536 | 0.74 | MAPT (0.66) | MAPTPOLBSMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL2853354 | 0.74 | P2RX7 (0.63) | P2RX7 | |
| SCHEMBL2850449 | 0.73 | SMN1; SMN2 (0.57) | MAPTPOLBSMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL24303276 | 0.73 | MAPT (0.61) | MAPTPOLBSMN1; SMN2PTPN1KDM4E | |
| SCHEMBL2858203 | 0.73 | MAPT (0.68) | MAPTPOLBSMN1; SMN2PTPN1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | disclosed |