Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 6/20 | 0.66 |
| ▸ | TRPC3 | Q13507 | 1/20 | 0.51 |
| ▸ | CCR1 | P32246 | 7/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.48 |
| ▸ | DGAT2 | Q96PD7 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2848290 | 0.88 | P2RX7 (0.60) | P2RX7TRPC3CCR1KDM4EALDH1A1 | |
| SCHEMBL2856181 | 0.85 | CCR1 (0.56) | P2RX7TRPC3CCR1KDM4EALDH1A1 | |
| SCHEMBL2853354 | 0.83 | P2RX7 (0.63) | P2RX7EPHX2 | |
| SCHEMBL2861063 | 0.83 | CCR1 (0.57) | P2RX7TRPC3CCR1KDM4EALDH1A1 | |
| SCHEMBL2858070 | 0.83 | CCR1 (0.57) | P2RX7TRPC3CCR1KDM4EALDH1A1 | |
| SCHEMBL2852038 | 0.82 | P2RX7 (0.53) | P2RX7TRPC3KDM4EALDH1A1 | |
| SCHEMBL2854422 | 0.82 | CCR1 (0.58) | P2RX7TRPC3CCR1KDM4EALDH1A1 | |
| SCHEMBL2850363 | 0.81 | CCR1 (0.59) | P2RX7TRPC3CCR1KDM4EALDH1A1 | |
| SCHEMBL2850016 | 0.80 | KDM4E (0.65) | P2RX7TRPC3KDM4EALDH1A1DGAT2 | |
| SCHEMBL2854425 | 0.80 | CCR1 (0.60) | TRPC3CCR1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | disclosed |