Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 12/20 | 0.63 |
| ▸ | EPHX2 | P34913 | 5/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2853184 | 0.91 | P2RX7 (0.54) | P2RX7TRPV1LMNA | |
| SCHEMBL2854563 | 0.89 | P2RX7 (0.57) | P2RX7LMNA | |
| SCHEMBL2850425 | 0.86 | P2RX7 (0.49) | P2RX7MAPK1 | |
| SCHEMBL2855322 | 0.86 | P2RX7 (0.47) | P2RX7EPHX2TRPV1LMNA | |
| SCHEMBL2860504 | 0.84 | P2RX7 (0.49) | P2RX7 | |
| SCHEMBL2852241 | 0.84 | MAPK1 (0.53) | P2RX7MAPK1LMNA | |
| SCHEMBL2851005 | 0.83 | P2RX7 (0.66) | P2RX7EPHX2 | |
| SCHEMBL2854707 | 0.83 | P2RX7 (0.45) | P2RX7EPHX2MAPK1TRPV1LMNA | |
| SCHEMBL2861423 | 0.83 | P2RX7 (0.46) | P2RX7 | |
| SCHEMBL2857989 | 0.82 | P2RX7 (0.49) | P2RX7LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |