Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | CETP | P11597 | 4/20 | 0.41 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6268172 | 0.98 | SIGMAR1 (0.44) | DNM1MEN1KMT2AEPHX2TP53 | |
| SCHEMBL27595305 | 0.92 | TP53 (0.42) | DNM1MEN1KMT2AEPHX2TP53 | |
| Fluoride SCHEMBL27912809 | 0.90 | TP53 (0.41) | DNM1MEN1KMT2AEPHX2TP53 | |
| Fluoride SCHEMBL27912810 | 0.90 | TP53 (0.41) | DNM1MEN1KMT2AEPHX2TP53 | |
| SCHEMBL19809460 | 0.83 | TP53 (0.46) | TP53SMN1; SMN2SIGMAR1 | |
| SCHEMBL24849454 | 0.82 | SIGMAR1 (0.50) | DNM1MEN1KMT2AEPHX2TP53 | |
| SCHEMBL9643733 | 0.82 | KCNH2 (0.59) | TP53KCNH2SIGMAR1CETP | |
| SCHEMBL31216299 | 0.82 | SIGMAR1 (0.50) | DNM1MEN1KMT2AEPHX2TP53 | |
| SCHEMBL31216281 | 0.82 | KCNH2 (0.54) | DNM1TP53KCNH2SIGMAR1CETP | |
| SCHEMBL5681515 | 0.79 | MAOA (0.54) | SMN1; SMN2SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112174995-B | Double-silicon compound, preparation method and application thereof | 武汉大学 | 2021-12-03 | — | — | CN | disclosed |
| CN-112174995-A | Double-silicon compound, preparation method and application thereof | 武汉大学 | 2021-01-05 | — | — | CN | disclosed |