Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.47 |
| ▸ | RAB9A | P51151 | 6/20 | 0.47 |
| ▸ | NPC1 | O15118 | 5/20 | 0.47 |
| ▸ | LMNA | P02545 | 6/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 9/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.45 |
| ▸ | RECQL | P46063 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28592291 | 0.82 | SMN1; SMN2 (0.46) | SMN1; SMN2RAB9ANPC1LMNAHTT | |
| SCHEMBL1267498 | 0.81 | SMN1; SMN2 (0.66) | SMN1; SMN2RAB9ANPC1LMNAHTT | |
| SCHEMBL28522554 | 0.77 | SMN1; SMN2 (0.54) | SMN1; SMN2RAB9ANPC1LMNAHTT | |
| SCHEMBL29954298 | 0.74 | SMN1; SMN2 (0.49) | SMN1; SMN2RAB9ANPC1LMNAHTT | |
| SCHEMBL28599185 | 0.74 | SMN1; SMN2 (0.46) | SMN1; SMN2RAB9ANPC1LMNAHTT | |
| SCHEMBL29953885 | 0.71 | MAPT (0.50) | SMN1; SMN2LMNAHTTMAPK1MAPT | |
| SCHEMBL730547 | 0.71 | MAPT (0.50) | SMN1; SMN2LMNAHTTMAPK1MAPT | |
| SCHEMBL11487535 | 0.70 | LMNA (0.74) | SMN1; SMN2RAB9ANPC1LMNAHTT | |
| SCHEMBL11384692 | 0.70 | MAPT (0.56) | SMN1; SMN2RAB9ANPC1LMNAHTT | |
| SCHEMBL15329692 | 0.70 | MAPT (0.54) | SMN1; SMN2RAB9ANPC1LMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108017618-B | Novel compound pyrazole aldehyde pyridine amine Schiff base and preparation method and application thereof | 淮阴师范学院 | 2021-02-09 | — | — | CN | disclosed |