Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TET2 | Q6N021 | 1/20 | 0.46 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | FNTA | P49354 | 1/20 | 0.43 |
| ▸ | FNTB | P49356 | 1/20 | 0.43 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.43 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.42 |
| ▸ | PPARG | P37231 | 7/20 | 0.42 |
| ▸ | PPARD | Q03181 | 7/20 | 0.42 |
| ▸ | PPARA | Q07869 | 7/20 | 0.42 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.42 |
| ▸ | TSHR | P16473 | 4/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | TLR2 | O60603 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | FABP4 | P15090 | 2/20 | 0.42 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.42 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3893852 | 0.98 | THRB (0.46) | TET2AKR1B1THRBFNTAFNTB | |
| SCHEMBL17183933 | 0.98 | THRB (0.46) | TET2AKR1B1THRBFNTAFNTB | |
| Methacrylic Acid SCHEMBL5068568 | 0.95 | FNTA (0.43) | TET2AKR1B1THRBFNTAFNTB | |
| Methacrylic Acid SCHEMBL6434857 | 0.93 | FNTA (0.46) | TET2AKR1B1THRBFNTAFNTB | |
| SCHEMBL6910249 | 0.86 | AKR1B1 (0.56) | AKR1B1THRBFNTAFNTBPGGT1B | |
| SCHEMBL22545 | 0.86 | AKR1B1 (0.56) | AKR1B1THRBFNTAFNTBPGGT1B | |
| SCHEMBL147810 | 0.84 | GPR84 (0.58) | AKR1B1THRBFNTAFNTBPGGT1B | |
| SCHEMBL1119569 | 0.84 | GPR84 (0.58) | AKR1B1THRBFNTAFNTBPGGT1B | |
| SCHEMBL3947983 | 0.84 | GPR84 (0.58) | AKR1B1THRBFNTAFNTBPGGT1B | |
| SCHEMBL148286 | 0.84 | GPR84 (0.58) | AKR1B1THRBFNTAFNTBPGGT1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120328677-A1 | Active Agent Formulations, Methods of Making, and Methods of Use | MUTUAL PHARMACEUTICAL COMPANY, INC. (US) | 2012-12-27 | — | — | US | disclosed |
| EP-2152758-B1 | NITRILE RUBBERS | LANXESS DEUTSCHLAND GMBH (DE) | 2012-09-26 | — | — | EP | disclosed |
| EP-1868736-B9 | COATING COMPOSITIONS CONTAINING HIGHLY CROSSLINKED POLYMER PARTICLES AND A HYDROPHOBIC POLYMER | PPG IND OHIO INC (US) | 2010-07-14 | — | — | EP | disclosed |
| US-20100159010-A1 | Active Agent Formulations, Methods of Making, and Methods of Use | MUTUAL PHARMACEUTICAL COMPANY, INC. (US) | 2010-06-24 | — | — | US | disclosed |
| EP-1868736-B1 | COATING COMPOSITIONS CONTAINING HIGHLY CROSSLINKED POLYMER PARTICLES AND A HYDROPHOBIC POLYMER | PPG IND OHIO INC (US) | 2009-08-26 | — | — | EP | disclosed |
| US-20080050450-A1 | Active Agent Formulations, Methods of Making, and Methods of Use | MUTUAL PHARMACEUTICAL COMPANY, INC. (US) | 2008-02-28 | — | — | US | disclosed |
| EP-1868736-A1 | COATING COMPOSITIONS CONTAINING HIGHLY CROSSLINKED POLYMER PARTICLES AND A HYDROPHOBIC POLYMER | PPG Industries Ohio, Inc. (US) | 2007-12-26 | — | — | EP | disclosed |
| WO-2006104664-A1 | COATING COMPOSITIONS CONTAINING HIGHLY CROSSLINKED POLYMER PARTICLES AND A HYDROPHOBIC POLYMER | PPG INDUSTRIES OHIO, INC. (US) | 2006-10-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120328677-A1 | Active Agent Formulations, Methods of Making, and Methods of Use | CEL, IDUA, SI | TET2 2323/4885AKR1B1 2737/4885THRB 2803/4885 |
| US-20100159010-A1 | Active Agent Formulations, Methods of Making, and Methods of Use | CEL, IDUA, SI | TET2 2323/4885AKR1B1 2737/4885THRB 2803/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.