Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | CA12 | O43570 | 2/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | CA9 | Q16790 | 2/20 | 0.44 |
| ▸ | AR | P10275 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | VDR | P11473 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | STAT3 | P40763 | 1/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16283692 | 0.86 | MEN1 (0.51) | MEN1KMT2AALDH1A1FFAR1HTT | |
| SCHEMBL28514304 | 0.85 | MEN1 (0.54) | MEN1KMT2AALDH1A1LMNACA12 | |
| SCHEMBL28513058 | 0.82 | MEN1 (0.48) | MEN1KMT2AALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL16020645 | 0.80 | MAPT (0.44) | MEN1KMT2AALDH1A1LMNACA12 | |
| SCHEMBL8871679 | 0.80 | STAT3 (0.43) | KMT2AALDH1A1HTTSMN1; SMN2LMNA | |
| SCHEMBL1866694 | 0.79 | ALDH1A1 (0.46) | MEN1KMT2AALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL27193057 | 0.78 | MEN1 (0.49) | MEN1KMT2AALDH1A1FFAR1HTT | |
| SCHEMBL139911 | 0.77 | CA12 (0.41) | MEN1KMT2AALDH1A1CA12CA1 | |
| SCHEMBL8673256 | 0.77 | MEN1 (0.57) | MEN1KMT2AALDH1A1FFAR1HTT | |
| SCHEMBL23703227 | 0.76 | GAA (0.43) | MEN1KMT2AALDH1A1HTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4662219-A2 | PRODRUGS OF THYROID HORMONE ANALOGS, METHODS OF MAKING AND METHODS OF USING THEREOF | ASCLETIS PHARMA (CHINA) CO., LIMITED (HK) | 2025-12-17 | — | — | EP | disclosed |
| US-20240294561-A1 | Prodrugs of Thyroid Hormone Analogs, Methods of Making and Methods of Using Thereof | ASCLETIS PHARMA (CHINA) CO., LIMITED (CN) | 2024-09-05 | — | — | US | disclosed |
| WO-2024167961-A2 | PRODRUGS OF THYROID HORMONE ANALOGS, METHODS OF MAKING AND METHODS OF USING THEREOF | GANNEX, LLC (US) | 2024-08-15 | — | — | WO | disclosed |
| CN-115677774-A | Phosphonate derivatives, their preparation and use | 上海医药工业研究院有限公司 | 2023-02-03 | — | — | CN | disclosed |
| CN-114409706-A | Preparation method of phenyl hydrogen phosphonate and intermediate thereof | 上海医药工业研究院 | 2022-04-29 | — | — | CN | disclosed |
| CN-112175003-B | Preparation method of phenyl hydrogen phosphonate and intermediate thereof | 上海医药工业研究院 | 2022-02-15 | — | — | CN | disclosed |
| CN-112175003-A | Preparation method of phenyl hydrogen phosphonate and intermediate thereof | 上海医药工业研究院 | 2021-01-05 | — | — | CN | disclosed |
| CN-108409788-B | Preparation method of tenofovir alafenamide fumarate | 科兴生物制药股份有限公司 | 2020-05-08 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240294561-A1 | Prodrugs of Thyroid Hormone Analogs, Methods of Making and Methods of Using Thereof | THRB, THRA, TSHR | MEN1 712/4885KMT2A 2974/4885ALDH1A1 1710/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.