Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLS | O94925 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.42 |
| ▸ | ATF4 | P18848 | 1/20 | 0.42 |
| ▸ | KDM1A | O60341 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.41 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 4/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24225718 | 1.00 | GLS (0.48) | GLSCYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL21882373 | 0.89 | ATF4 (0.44) | GLSCYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL23920621 | 0.88 | KMT2A (0.58) | GLSCYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL21050174 | 0.83 | KMT2A (0.54) | GLSCYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL24225710 | 0.82 | MEN1 (0.53) | GLSCYP1A2CYP3A4CYP2C9CYP2C19 | |
| Trifluoroacetic Acid SCHEMBL21050152 | 0.78 | GLS (0.47) | GLSCYP1A2CYP3A4CYP2C9CYP2C19 | |
| Trifluoroacetic Acid SCHEMBL21050151 | 0.78 | GLS (0.47) | GLSCYP1A2CYP3A4CYP2C9CYP2C19 | |
| Trifluoroacetic Acid SCHEMBL21062228 | 0.78 | GLS (0.47) | GLSCYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL23920263 | 0.78 | GLS (0.51) | GLSCYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL29988146 | 0.76 | ADAMTS5 (0.49) | CYP1A2CYP3A4CYP2C9CYP2C19KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111757739-A | Integrated stress pathway inhibitors | 普拉西斯生物技术有限责任公司 | 2020-10-09 | — | — | CN | disclosed |