Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 8/20 | 0.56 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | STAT6 | P42226 | 3/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28518019 | 0.90 | PPARG (0.62) | PPARGHDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL28518879 | 0.86 | SMN1; SMN2 (0.58) | PPARGRAB9ANPC1SMN1; SMN2CYP1A2 | |
| SCHEMBL28533016 | 0.73 | EGLN1 (0.41) | HDAC3HDAC1HDAC2HDAC6HDAC8 | |
| SCHEMBL1522370 | 0.73 | PPARG (0.62) | PPARGSMN1; SMN2THRBSTAT6AGTR1 | |
| SCHEMBL12904539 | 0.71 | STAT6 (0.58) | PPARGTHRBSTAT6JAK2JAK1 | |
| SCHEMBL28523854 | 0.70 | HDAC1 (0.45) | HDAC1HDAC6RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL445955 | 0.70 | ALDH1A1 (0.65) | PPARGRAB9ANPC1SMN1; SMN2CYP1A2 | |
| SCHEMBL34462302 | 0.69 | AGTR1 (0.51) | PPARGHDAC3RAB9ASMN1; SMN2MAPT | |
| SCHEMBL28522379 | 0.69 | PDE4A (0.53) | SMN1; SMN2MAPTNPSR1AGTR1AGTR2 | |
| SCHEMBL28518021 | 0.67 | PDE4A (0.56) | SMN1; SMN2MAPTNPSR1AGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106279044-B | Pyrimidine hydroxamic acid derivative and preparation method and application thereof | 厦门市博瑞来医药科技有限公司 | 2021-02-19 | — | — | CN | disclosed |