Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 8/20 | 0.62 |
| ▸ | AGTR1 | P30556 | 5/20 | 0.48 |
| ▸ | AGTR2 | P50052 | 5/20 | 0.48 |
| ▸ | KDM5B | Q9UGL1 | 3/20 | 0.45 |
| ▸ | KDM6B | O15054 | 2/20 | 0.45 |
| ▸ | KDM4A | O75164 | 2/20 | 0.45 |
| ▸ | KDM4D | Q6B0I6 | 2/20 | 0.45 |
| ▸ | KDM3B | Q7LBC6 | 2/20 | 0.45 |
| ▸ | HIF1AN | Q9NWT6 | 2/20 | 0.45 |
| ▸ | KDM2A | Q9Y2K7 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | PLK1 | P53350 | 1/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28522378 | 0.90 | PPARG (0.56) | PPARGAGTR1AGTR2NPC1CYP1A2 | |
| SCHEMBL28518879 | 0.89 | SMN1; SMN2 (0.58) | PPARGAGTR1AGTR2NPC1CYP1A2 | |
| SCHEMBL1522370 | 0.82 | PPARG (0.62) | PPARGAGTR1AGTR2KDM5BKDM6B | |
| SCHEMBL34462302 | 0.78 | AGTR1 (0.51) | PPARGAGTR1AGTR2KDM5BMAPT | |
| SCHEMBL1014882 | 0.73 | RAB9A (0.42) | KDM5BKDM6BKDM4AKDM4DKDM3B | |
| SCHEMBL12904539 | 0.73 | STAT6 (0.58) | PPARG | |
| SCHEMBL28524818 | 0.72 | ALDH1A1 (0.42) | NPC1MAPTRAB9ASMN1; SMN2HDAC3 | |
| SCHEMBL445955 | 0.72 | ALDH1A1 (0.65) | PPARGNPC1CYP1A2CYP2D6MAPT | |
| SCHEMBL16824948 | 0.70 | KDM4E (0.54) | PPARG | |
| SCHEMBL2894732 | 0.70 | AGTR2 (0.53) | AGTR1AGTR2KDM5BKDM6BKDM4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106279044-B | Pyrimidine hydroxamic acid derivative and preparation method and application thereof | 厦门市博瑞来医药科技有限公司 | 2021-02-19 | — | — | CN | disclosed |