Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.41 |
| ▸ | MMP13 | P45452 | 4/20 | 0.41 |
| ▸ | MMP1 | P03956 | 2/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.41 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | MMP14 | P50281 | 1/20 | 0.41 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.41 |
| ▸ | MMP9 | P14780 | 3/20 | 0.40 |
| ▸ | ADAM17 | P78536 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 2/20 | 0.40 |
| ▸ | CA9 | Q16790 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | PTGES | O14684 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28524818 | 0.91 | ALDH1A1 (0.42) | EGLN1HDAC1MAPTMEN1KMT2A | |
| SCHEMBL28525182 | 0.88 | SMN1; SMN2 (0.52) | MAPTMEN1KMT2ATP53HSD17B10 | |
| SCHEMBL28533018 | 0.74 | HSD17B10 (0.44) | EGLN1MMP13MMP1HDAC1ADAMTS4 | |
| SCHEMBL28522378 | 0.73 | PPARG (0.56) | HDAC1MAPTHDAC3HDAC2HDAC8 | |
| SCHEMBL28524820 | 0.72 | ALDH1A1 (0.44) | EGLN1MMP13MMP1MMP9ADAM17 | |
| SCHEMBL28525183 | 0.70 | ALDH1A1 (0.44) | EGLN1MAPTMEN1KMT2ATP53 | |
| SCHEMBL28523854 | 0.66 | HDAC1 (0.45) | HDAC1MEN1KMT2AHSD17B10HDAC6 | |
| SCHEMBL11061920 | 0.65 | PTGES (0.66) | MAPTMEN1KMT2AHSD17B10PTGES | |
| SCHEMBL7320167 | 0.63 | FFAR4 (0.70) | MMP13MMP1MMP2MMP14MMP9 | |
| SCHEMBL15482273 | 0.62 | HDAC3 (0.68) | HDAC1MAPTMEN1KMT2ATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106279044-B | Pyrimidine hydroxamic acid derivative and preparation method and application thereof | 厦门市博瑞来医药科技有限公司 | 2021-02-19 | — | — | CN | disclosed |