SCHEMBL2852255

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2858714	0.83	MAPT (0.49)	ALDH1A1TDP1CYP1A2CES2CES1
	SCHEMBL2117704	0.83	KMT2A (0.49)	ALDH1A1TDP1CA1CA2CA12
	SCHEMBL277081	0.83	SMN1; SMN2 (0.48)	ALDH1A1TDP1CA1CA2CA12
	SCHEMBL2775303	0.83	USP2 (0.48)	HDAC3HDAC4HDAC1HDAC7HDAC2
	SCHEMBL2775301	0.83	USP2 (0.48)	HDAC3HDAC4HDAC1HDAC7HDAC2
	SCHEMBL1741190	0.83	ALDH1A1 (0.53)	ALDH1A1CA1CA2CA12CA9
	SCHEMBL4800700	0.82	SMN1; SMN2 (0.47)	ALDH1A1TDP1CA1CA2CA12
	SCHEMBL14346527	0.81	CA12 (0.36)	ALDH1A1TDP1CA1CA2CA12
	SCHEMBL16883572	0.80	KMT2A (0.43)	ALDH1A1CYP1A2HTTLMNAL3MBTL1
	SCHEMBL5217024	0.80	CES2 (0.61)	HDAC3HDAC4HDAC1HDAC7HDAC2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.