Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Asparagine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Asparagine SCHEMBL28801819 | 0.93 | CD274 (0.33) | PDCD1LG2CD274 | |
| Asparagine SCHEMBL3442870 | 0.92 | SLC7A5 (0.35) | — | |
| Glutamine SCHEMBL28152470 | 0.92 | ALOX15 (0.35) | — | |
| Threonine SCHEMBL28072332 | 0.91 | — | — | |
| Asparagine SCHEMBL5666134 | 0.90 | SLC7A5 (0.33) | — | |
| Leucine SCHEMBL29042983 | 0.89 | SLC7A5 (0.38) | PDCD1LG2CD274 | |
| Threonine SCHEMBL6520767 | 0.89 | — | — | |
| Threonine SCHEMBL6520771 | 0.89 | — | — | |
| Asparagine SCHEMBL28801799 | 0.89 | NOS2 (0.33) | — | |
| Asparagine SCHEMBL4995025 | 0.89 | NOS2 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112225794-A | FGFRL1 Giraffe mutant protein and coding gene and application thereof | 中国人民解放军空军军医大学 | 2021-01-15 | — | — | CN | claimed |
| CN-112225794-B | FGFRL1 Giraffe mutant protein, coding gene and application thereof | 中国人民解放军空军军医大学 | 2022-10-11 | — | — | CN | disclosed |
| CN-112225794-A | FGFRL1 Giraffe mutant protein and coding gene and application thereof | 中国人民解放军空军军医大学 | 2021-01-15 | — | — | CN | disclosed |