Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSF1R | P07333 | 7/20 | 0.53 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.49 |
| ▸ | MERTK | Q12866 | 1/20 | 0.49 |
| ▸ | GAS6 | Q14393 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.46 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.46 |
| ▸ | BCL3 | P20749 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28527136 | 0.95 | CSF1R (0.56) | CSF1RKDM4EALDH1A1HPGDLMNA | |
| SCHEMBL28527347 | 0.90 | CSF1R (0.57) | CSF1RPOLBGAAKDM4EALDH1A1 | |
| SCHEMBL3290854 | 0.87 | CSF1R (0.56) | CSF1RTYRO3MERTKGAS6KDM4E | |
| SCHEMBL4796017 | 0.87 | CSF1R (0.59) | CSF1RTYRO3MERTKGAS6POLB | |
| SCHEMBL3293656 | 0.85 | CSF1R (0.69) | CSF1RTYRO3MERTKGAS6 | |
| SCHEMBL28536148 | 0.85 | CSF1R (0.58) | CSF1R | |
| SCHEMBL3290842 | 0.84 | CSF1R (0.62) | CSF1RMERTK | |
| SCHEMBL3290585 | 0.82 | CSF1R (0.54) | CSF1RPOLBKDM4EALDH1A1HSD17B10 | |
| SCHEMBL3290621 | 0.82 | CSF1R (0.75) | CSF1RMERTK | |
| SCHEMBL28530641 | 0.81 | CSF1R (0.62) | CSF1RALDH1A1TSHRHSD17B10MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111848613-A | Diaryl pyrimidopyridinone derivative and preparation method and application thereof | 山东大学 | 2020-10-30 | — | — | CN | claimed |
| CN-111848613-B | Diaryl pyrimidopyridinone derivative and preparation method and application thereof | 山东大学 | 2021-09-24 | — | — | CN | disclosed |
| CN-111848613-A | Diaryl pyrimidopyridinone derivative and preparation method and application thereof | 山东大学 | 2020-10-30 | — | — | CN | disclosed |