Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LDHA | P00338 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.34 |
| ▸ | COMT | P21964 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | EP300 | Q09472 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.33 |
| ▸ | TNNT2 | P45379 | 1/20 | 0.33 |
| ▸ | TNNC1 | P63316 | 1/20 | 0.33 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14927 | 0.99 | LDHA (0.41) | LDHAMEN1KMT2ATP53MAPK1 | |
| SCHEMBL16412126 | 0.94 | DNM1 (0.43) | LDHAMEN1KMT2ATP53MAPK1 | |
| SCHEMBL16412124 | 0.93 | LDHA (0.44) | LDHAMEN1KMT2AGAATHRB | |
| Tetrabuthylammonium SCHEMBL16412173 | 0.89 | LDHA (0.47) | LDHAMEN1KMT2AGAATHRB | |
| SCHEMBL10383940 | 0.89 | NR4A1 (0.46) | MEN1KMT2ATP53MAPK1SMN1; SMN2 | |
| SCHEMBL446313 | 0.88 | TNNI3 (0.44) | LDHAMEN1KMT2ATP53MAPK1 | |
| SCHEMBL10382892 | 0.88 | NR4A1 (0.40) | LDHAMEN1KMT2ATP53MAPK1 | |
| SCHEMBL2533438 | 0.87 | LDHA (0.45) | LDHAMEN1KMT2AGAATHRB | |
| SCHEMBL180944 | 0.85 | HKDC1 (0.41) | MEN1KMT2ATP53MAPK1SMN1; SMN2 | |
| SCHEMBL9503533 | 0.85 | NSD2 (0.38) | MEN1KMT2ATP53MAPK1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107247394-B | Carbon powder for heating fixing process and preparation method thereof | 湖北远东卓越科技股份有限公司 | 2020-12-29 | — | — | CN | claimed |
| CN-107247394-B | Carbon powder for heating fixing process and preparation method thereof | 湖北远东卓越科技股份有限公司 | 2020-12-29 | — | — | CN | disclosed |