Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | TGM2 | P21980 | 1/20 | 0.49 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.48 |
| ▸ | PARP1 | P09874 | 1/20 | 0.48 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15331088 | 0.78 | SMN1; SMN2 (0.55) | KMT2AMEN1LMNASMN1; SMN2KDM4E | |
| SCHEMBL10768094 | 0.78 | RAB9A (0.71) | KMT2AMEN1LMNASMN1; SMN2KDM4E | |
| SCHEMBL28508124 | 0.78 | LMNA (0.54) | KMT2AMEN1LMNASMN1; SMN2KDM4E | |
| SCHEMBL1240947 | 0.75 | LMNA (0.66) | KMT2AMEN1LMNASMN1; SMN2HTT | |
| SCHEMBL11526389 | 0.75 | TGM2 (0.62) | TGM2NPC1RAB9APKM | |
| SCHEMBL13927087 | 0.74 | PARP1 (0.49) | KMT2AMEN1LMNASMN1; SMN2KDM4E | |
| SCHEMBL3917825 | 0.74 | EPHX2 (0.54) | KMT2AMEN1LMNASMN1; SMN2KDM4E | |
| SCHEMBL13927084 | 0.74 | PARP1 (0.49) | KMT2AMEN1LMNASMN1; SMN2KDM4E | |
| SCHEMBL28668472 | 0.74 | SMN1; SMN2 (0.48) | KMT2AMEN1SMN1; SMN2KDM4EHTT | |
| SCHEMBL6972945 | 0.74 | PARP1 (0.49) | KMT2AMEN1LMNASMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108503650-B | Dioxane and quinazoline compound or medicinal salt or hydrate thereof and application of dioxane and quinazoline compound or medicinal salt or hydrate thereof as tyrosine kinase inhibitor | 北京赛特明强医药科技有限公司 | 2021-02-12 | — | — | CN | disclosed |