Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | CA12 | O43570 | 4/20 | 0.41 |
| ▸ | CA2 | P00918 | 4/20 | 0.41 |
| ▸ | CA9 | Q16790 | 4/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.41 |
| ▸ | TYR | P14679 | 3/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | CA1 | P00915 | 3/20 | 0.41 |
| ▸ | CA7 | P43166 | 2/20 | 0.41 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | MIF | P14174 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | LCK | P06239 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL4584444 | 1.00 | ALOX5 (0.44) | ALOX5HSD17B10ALDH1A1CA12CA2 | |
| SCHEMBL10793095 | 0.97 | — | — | |
| Water SCHEMBL9053915 | 0.94 | ALOX5 (0.44) | ALOX5HSD17B10ALDH1A1CA12CA2 | |
| Biphenyl SCHEMBL27639430 | 0.84 | ALOX5 (0.56) | ALOX5HSD17B10ALDH1A1ALOX15LMNA | |
| Chloroacetic Acid SCHEMBL11577602 | 0.79 | CA2 (0.44) | ALOX5HSD17B10ALDH1A1CA12CA2 | |
| SCHEMBL29829218 | 0.76 | — | — | |
| SCHEMBL4862349 | 0.76 | ALOX5 (0.60) | ALOX5HSD17B10ALDH1A1CA12CA2 | |
| SCHEMBL33527 | 0.76 | — | — | |
| SCHEMBL19119600 | 0.74 | — | — | |
| Phosphine SCHEMBL11514630 | 0.73 | ALOX5 (0.57) | ALOX5HSD17B10ALDH1A1CA12CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108476589-B | Dry film and printed circuit board | 太阳油墨制造株式会社 | 2021-10-26 | — | — | CN | disclosed |
| CN-112368416-A | Flexible copper clad laminate and preparation method thereof | 东丽尖端素材株式会社 | 2021-02-12 | — | — | CN | disclosed |