SCHEMBL28524455

SCHEMBL28524455

Nc1ccc(-n2nccn2)c(O)c1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CASP1 P29466 2/20 0.42
TSHR P16473 1/20 0.42
KDM4E B2RXH2 6/20 0.38
MAPT P10636 5/20 0.38
ALDH1A1 P00352 5/20 0.38
GAA P10253 3/20 0.38
CYP3A4 P08684 2/20 0.38
ESR2 Q92731 1/20 0.38
PTPN1 P18031 1/20 0.38
CA1 P00915 1/20 0.38
CA2 P00918 1/20 0.38
PDE10A Q9Y233 1/20 0.38
MEN1 O00255 4/20 0.37
KMT2A Q03164 4/20 0.37
ALOX15 P16050 3/20 0.36
TDP1 Q9NUW8 3/20 0.36
HSD17B10 Q99714 2/20 0.36
POLB P06746 1/20 0.36
MAPK1 P28482 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29793409 1.00 CASP1 (0.42) CASP1TSHRKDM4EMAPTALDH1A1
SCHEMBL28530940 0.84 MEN1 (0.43) CASP1TSHRKDM4EMAPTALDH1A1
SCHEMBL2627309 0.76 ALDH1A1 (0.55) CASP1TSHRKDM4EMAPTALDH1A1
SCHEMBL17293131 0.76 MAPT (0.53) CASP1TSHRKDM4EMAPTALDH1A1
SCHEMBL14320459 0.76 ALDH1A1 (0.45) TSHRKDM4EMAPTALDH1A1GAA
SCHEMBL30884183 0.76 MAPT (0.53) CASP1TSHRKDM4EMAPTALDH1A1
SCHEMBL28546258 0.76 ABAT (0.38) KDM4EMAPTALDH1A1GAAMEN1
SCHEMBL3937549 0.76 NPC1 (0.51) CASP1TSHRKDM4EMAPTALDH1A1
SCHEMBL30058950 0.76 NPC1 (0.51) CASP1TSHRKDM4EMAPTALDH1A1
SCHEMBL19817407 0.73 GAA (0.52) CASP1TSHRKDM4EMAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114714724-B Hot melt adhesive transfer film and preparation method thereof 云阳金田塑业有限公司 2023-11-17 CN claimed
CN-114714724-A Hot melt adhesive transfer film and preparation method thereof 云阳金田塑业有限公司 2022-07-08 CN claimed
CN-114714724-B Hot melt adhesive transfer film and preparation method thereof 云阳金田塑业有限公司 2023-11-17 CN disclosed
CN-114714724-A Hot melt adhesive transfer film and preparation method thereof 云阳金田塑业有限公司 2022-07-08 CN disclosed
CN-108842932-B High-adhesion polyolefin anti-adhesion film and preparation method thereof 江苏优珀斯材料科技有限公司 2021-03-19 CN disclosed