SCHEMBL2852465

SCHEMBL2852465

O=C(O)C=C(CCO)C(=O)O

nearest known ligand 0.54

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.54
TSHR P16473 1/20 0.54
ATM Q13315 1/20 0.32
CAMK2A Q9UQM7 1/20 0.32
FNTA P49354 1/20 0.31
FNTB P49356 1/20 0.31
ABAT P80404 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9410888 1.00 KDM4E (0.54) KDM4ETSHRATMCAMK2AFNTA
SCHEMBL5981768 1.00 KDM4E (0.54) KDM4ETSHRATMCAMK2AFNTA
SCHEMBL9410883 1.00 KDM4E (0.54) KDM4ETSHRATMCAMK2AFNTA
SCHEMBL4532099 1.00 KDM4E (0.54) KDM4ETSHRATMCAMK2AFNTA
Acrylic Acid SCHEMBL30645722 0.91 TSHR (0.46) KDM4ETSHR
SCHEMBL28488698 0.86 TSHR (0.62) KDM4ETSHRATMABAT
SCHEMBL8951267 0.85 KDM4E (0.50) KDM4ETSHRATMCAMK2AFNTA
SCHEMBL9309370 0.85 KDM4E (0.50) KDM4ETSHRATMCAMK2AFNTA
SCHEMBL8951262 0.85 KDM4E (0.50) KDM4ETSHRATMCAMK2AFNTA
SCHEMBL9410884 0.82 KDM4E (0.39) KDM4ETSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0274270-A1 Optical recording material AGENCY OF INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) 1988-07-13 EP claimed
US-4065423-A Paper coating latex compositions containing copolymers of monovinylidene aromatic monomer, aliphatic conjugated diene and an aryloyloxycarboxylic acid monomer UNIROYAL, INC. (US) 1977-12-27 US claimed
EP-4581088-A1 COATING COMPOSITIONS INCLUDING AN ACRYLIC POLYMER AND A PHENOLIC CROSSLINKER, ARTICLES, ACRYLIC POLYMERS, AND METHODS SWIMC LLC (US) 2025-07-09 EP disclosed
WO-2024050037-A1 COATING COMPOSITIONS INCLUDING AN ACRYLIC POLYMER AND A PHENOLIC CROSSLINKER, ARTICLES, ACRYLIC POLYMERS, AND METHODS SWIMC LLC (US) 2024-03-07 WO disclosed
EP-3569591-A1 HIGH HEAT MONOMERS AND METHODS OF USE THEREOF SABIC Global Technologies B.V. (NL) 2019-11-20 EP disclosed
US-20190337895-A1 HIGH HEAT MONOMERS AND METHODS OF USE THEREOF SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2019-11-07 US disclosed
US-10435368-B2 High heat monomers and methods of use thereof SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2019-10-08 US disclosed
EP-3172188-B1 HIGH HEAT MONOMERS AND METHODS OF USE THEREOF SABIC GLOBAL TECHNOLOGIES BV (NL) 2019-09-04 EP disclosed
US-20180179499-A1 BIOBASED PRODUCTION OF FUNCTIONALIZED ALPHA-SUBSTITUTED ACRYLATES AND C4-DICARBOXYLATES LCY BIOSCIENCES INC. (CA) 2018-06-28 US disclosed
EP-3303375-A1 BIOBASED PRODUCTION OF FUNCTIONALIZED ALPHA-SUBSTITUTED ACRYLATES AND C4-DICARBOXYLATES BioAmber Inc. (US) 2018-04-11 EP disclosed
US-20170166528-A1 HIGH HEAT MONOMERS AND METHODS OF USE THEREOF SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2017-06-15 US disclosed
EP-0274270-A1 Optical recording material AGENCY OF INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) 1988-07-13 EP disclosed
EP-0255988-A2 Particulate hydroperoxidized poly -N-vinyl lactam, its preparation and use thereof CIBA-GEIGY AG (CH) 1988-02-17 EP disclosed
US-4617343-A ACRYLIC RESINS INCLUDING SULFO UNSATURATED MONOMERS; ALCOHOL-DILUTABLE; NONSMEARING OF PRINTER SURFACES NATIONAL STARCH AND CHEMICAL CORPORATION (US) 1986-10-14 US disclosed
US-4567083-A BACK COATING FO THERMOSETTING RESIN OR RADIATION CURABLE COMPOSITION TDK CORPORATION (JP) 1986-01-28 US disclosed
US-4343831-A DISPERSION OF FERROMAGNETIC PARTICLES IN BINDER CURABLE BY RADIATION WITH ELECTRONS FUJI PHOTO FILM CO., LTD. (JP) 1982-08-10 US disclosed
US-4065423-A Paper coating latex compositions containing copolymers of monovinylidene aromatic monomer, aliphatic conjugated diene and an aryloyloxycarboxylic acid monomer UNIROYAL, INC. (US) 1977-12-27 US disclosed
US-4065423-A Paper coating latex compositions containing copolymers of monovinylidene aromatic monomer, aliphatic conjugated diene and an aryloyloxycarboxylic acid monomer UNIROYAL, INC. (US) 1977-12-27 US disclosed
US-3991028-A ELECTRODEPOSITABLE, H3991028 MOD 3991028 YDROXYLALKYL ACRYLATE INTERPOLYMER, AMINE-ALDEHYDE CONDENSATE PPG INDUSTRIES, INC. (US) 1976-11-09 US disclosed
US-3956091-A METAL FOOD CONTAINERS, RESISTANT TO SULFIDE STAINING PPG INDUSTRIES, INC. (US) 1976-05-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190337895-A1 HIGH HEAT MONOMERS AND METHODS OF USE THEREOF HSP90AA1, HSP90AB1, HSPBP1 KDM4E 4787/4885TSHR 4844/4885ATM 985/4885
US-20180179499-A1 BIOBASED PRODUCTION OF FUNCTIONALIZED ALPHA-SUBSTITUTED ACRYLATES AND C4-DICARBOXYLATES COASY, ADSL, ALAD KDM4E 3251/4885TSHR 3786/4885ATM 2183/4885
US-20170166528-A1 HIGH HEAT MONOMERS AND METHODS OF USE THEREOF HSP90AA1, HSP90AB1, HSPBP1 KDM4E 4787/4885TSHR 4844/4885ATM 985/4885
US-10435368-B2 High heat monomers and methods of use thereof HSP90AA1, HSP90AB1, HSPBP1 KDM4E 4787/4885TSHR 4844/4885ATM 985/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.