Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPBWR1 | P48145 | 2/20 | 0.42 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.42 |
| ▸ | CCR1 | P32246 | 6/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | SMO | Q99835 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2854330 | 0.92 | CCR1 (0.52) | CCR1RECQLUSP2POLBFAAH | |
| SCHEMBL2857994 | 0.91 | MTOR (0.46) | CCR1ALDH1A1KDM4ENPSR1 | |
| SCHEMBL2863210 | 0.89 | CCR1 (0.50) | CCR1SMOKDM4ENPSR1MAPK1 | |
| SCHEMBL2852520 | 0.88 | TP53 (0.47) | HPGDALDH1A1KDM4EPOLBGAA | |
| SCHEMBL2853270 | 0.88 | CCR1 (0.51) | CCR1NPSR1 | |
| SCHEMBL2857073 | 0.88 | CCR1 (0.48) | CCR1ALDH1A1KDM4EPOLB | |
| SCHEMBL2860466 | 0.87 | RCE1 (0.47) | CCR1SMOALDH1A1POLBGAA | |
| SCHEMBL2856797 | 0.86 | P2RX7 (0.45) | CCR1SMOALDH1A1MAPK1 | |
| SCHEMBL2848661 | 0.86 | ABCB1 (0.48) | NPBWR1CCR1ALDH1A1POLBTP53 | |
| SCHEMBL2856625 | 0.86 | TSHR (0.48) | NPBWR1CCR1SMONPSR1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |