Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 1/20 | 0.45 |
| ▸ | CCR1 | P32246 | 6/20 | 0.44 |
| ▸ | SMO | Q99835 | 8/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.38 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2853277 | 0.92 | CCR1 (0.50) | P2RX7CCR1SMO | |
| SCHEMBL2855623 | 0.91 | CCR1 (0.44) | P2RX7CCR1SMO | |
| SCHEMBL2860466 | 0.91 | RCE1 (0.47) | P2RX7CCR1SMOALDH1A1L3MBTL1 | |
| SCHEMBL2850314 | 0.91 | P2RX7 (0.42) | P2RX7CCR1SMOALDH1A1L3MBTL1 | |
| SCHEMBL2863210 | 0.87 | CCR1 (0.50) | P2RX7CCR1SMOMAPK1 | |
| SCHEMBL2852545 | 0.86 | NPBWR1 (0.42) | CCR1SMOALDH1A1MAPK1 | |
| SCHEMBL2853809 | 0.86 | P2RX7 (0.49) | P2RX7ALDH1A1 | |
| SCHEMBL2852356 | 0.85 | CCR1 (0.48) | P2RX7CCR1SMOMAPK1 | |
| SCHEMBL2855710 | 0.85 | LMNA (0.46) | P2RX7CCR1SMOMAPK1 | |
| SCHEMBL2854804 | 0.85 | MAPK1 (0.48) | P2RX7CCR1SMOALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |