Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | FAAH | O00519 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.43 |
| ▸ | SMO | Q99835 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | CCR1 | P32246 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2848661 | 0.91 | ABCB1 (0.48) | LMNAPOLBMAPTTP53CCR1 | |
| SCHEMBL2856797 | 0.91 | P2RX7 (0.45) | P2RX7SMOCCR1L3MBTL1ALDH1A1 | |
| SCHEMBL2852520 | 0.91 | TP53 (0.47) | GAAPOLBMAPTTP53MEN1 | |
| SCHEMBL2855710 | 0.90 | LMNA (0.46) | FAAHLMNAPOLBP2RX7SMO | |
| SCHEMBL2859091 | 0.89 | CCR1 (0.46) | P2RX7SMOCCR1 | |
| SCHEMBL2853277 | 0.89 | CCR1 (0.50) | LMNAPOLBP2RX7SMOTP53 | |
| SCHEMBL2850425 | 0.88 | P2RX7 (0.49) | POLBP2RX7SMOMAPTTP53 | |
| SCHEMBL2854847 | 0.88 | ALDH1A1 (0.48) | FAAHLMNAPOLBP2RX7SMO | |
| SCHEMBL2854804 | 0.88 | MAPK1 (0.48) | POLBP2RX7SMOMAPTTP53 | |
| SCHEMBL2852545 | 0.87 | NPBWR1 (0.42) | GAAFAAHPOLBSMOTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |