Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 9/20 | 0.50 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.47 |
| ▸ | SMO | Q99835 | 3/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MTOR | P42345 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | TACR1 | P25103 | 2/20 | 0.40 |
| ▸ | CCR2 | P41597 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2852356 | 0.96 | CCR1 (0.48) | CCR1P2RX7SMONPSR1KDM4E | |
| SCHEMBL2857994 | 0.94 | MTOR (0.46) | CCR1P2RX7NPSR1KDM4EMTOR | |
| SCHEMBL2853351 | 0.91 | CCR1 (0.62) | CCR1P2RX7NPSR1KDM4E | |
| SCHEMBL2853270 | 0.91 | CCR1 (0.51) | CCR1P2RX7NPSR1TACR1NPC1 | |
| SCHEMBL2859091 | 0.91 | CCR1 (0.46) | CCR1P2RX7SMOMAPK1NPC1 | |
| SCHEMBL2857073 | 0.91 | CCR1 (0.48) | CCR1KDM4ETACR1CCR2MAPT | |
| SCHEMBL2853349 | 0.89 | CCR1 (0.46) | CCR1KDM4EMAPK1TACR1MAPT | |
| SCHEMBL2852545 | 0.89 | NPBWR1 (0.42) | CCR1SMONPSR1KDM4EMAPK1 | |
| SCHEMBL2854804 | 0.88 | MAPK1 (0.48) | CCR1P2RX7SMOKDM4EMAPK1 | |
| SCHEMBL2858076 | 0.88 | MAPT (0.56) | CCR1NPSR1TACR1NPC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |