Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A2 | P31213 | 2/20 | 0.43 |
| ▸ | F2R | P25116 | 4/20 | 0.38 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.38 |
| ▸ | RXRA | P19793 | 1/20 | 0.38 |
| ▸ | RXRB | P28702 | 1/20 | 0.38 |
| ▸ | RXRG | P48443 | 1/20 | 0.38 |
| ▸ | P2RY14 | Q15391 | 5/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | CCR2 | P41597 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.37 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.37 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.36 |
| ▸ | LTA4H | P09960 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21616603 | 0.90 | SRD5A2 (0.43) | SRD5A2NOTUMRXRARXRBRXRG | |
| SCHEMBL28910602 | 0.87 | FPR1 (0.41) | SRD5A2F2RNOTUMP2RY14ADRA2A | |
| SCHEMBL28542508 | 0.86 | SRD5A2 (0.38) | SRD5A2F2RNOTUMRXRARXRB | |
| SCHEMBL23631891 | 0.85 | SRD5A2 (0.39) | SRD5A2F2RNOTUMRXRARXRB | |
| SCHEMBL28526814 | 0.85 | SRD5A2 (0.39) | SRD5A2F2RP2RY14PTGER4LTA4H | |
| SCHEMBL28540107 | 0.85 | SRD5A2 (0.39) | SRD5A2F2RNOTUMRXRARXRB | |
| SCHEMBL28533682 | 0.85 | SRD5A2 (0.39) | SRD5A2F2RNOTUMRXRARXRB | |
| SCHEMBL21616610 | 0.84 | SRD5A2 (0.38) | SRD5A2F2RP2RY14PTGER4LTA4H | |
| SCHEMBL28533463 | 0.84 | SRD5A2 (0.38) | SRD5A2F2RNOTUMP2RY14ADRA2A | |
| SCHEMBL28542875 | 0.83 | SRD5A2 (0.37) | SRD5A2F2RP2RY14ADRA2AADRA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112513021-B | ROR gamma antagonist and application thereof in medicines | 广东东阳光药业有限公司 | 2023-06-27 | — | — | CN | disclosed |
| CN-112513021-A | ROR gamma antagonist and application thereof in medicine | 广东东阳光药业有限公司 | 2021-03-16 | — | — | CN | disclosed |