SCHEMBL28525832

SCHEMBL28525832

Brc1cccc2c1-c1ccccc1C2Nc1cccc2ccccc12

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 4/20 0.37
KDM4E B2RXH2 4/20 0.37
TSHR P16473 4/20 0.37
MAPT P10636 3/20 0.37
SMN1; SMN2 Q16637 2/20 0.37
ALDH1A1 P00352 5/20 0.37
HSD17B10 Q99714 4/20 0.37
CYP3A4 P08684 2/20 0.37
TP53 P04637 1/20 0.37
ALOX15 P16050 1/20 0.37
CDC25B P30305 1/20 0.37
ATM Q13315 1/20 0.37
CASP3 P42574 2/20 0.36
SENP8 Q96LD8 2/20 0.36
SENP7 Q9BQF6 2/20 0.36
SENP6 Q9GZR1 2/20 0.36
APAF1 O14727 1/20 0.36
NSD2 O96028 1/20 0.36
GAA P10253 2/20 0.35
NPSR1 Q6W5P4 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19837583 0.84 ALDH1A1 (0.46) HPGDKDM4ETSHRMAPTSMN1; SMN2
SCHEMBL19837482 0.76 HPRT1 (0.48) HPGDKDM4ETSHRMAPTSMN1; SMN2
SCHEMBL13218576 0.73 DNMT1 (0.42) HPGDKDM4ETSHRMAPTSMN1; SMN2
SCHEMBL29040922 0.70 CYP2A6 (0.42) HPGDKDM4ETSHRMAPTSMN1; SMN2
SCHEMBL23443980 0.69 PBRM1 (0.36) MAPTSMN1; SMN2ALDH1A1CYP3A4GAA
SCHEMBL369327 0.67 DNMT1 (0.50) HPGDTSHRMAPTSMN1; SMN2ALDH1A1
SCHEMBL10384451 0.67 DNMT1 (0.50) TSHRMAPTSMN1; SMN2ALDH1A1HSD17B10
SCHEMBL30125426 0.67 DNMT1 (0.50) HPGDTSHRMAPTSMN1; SMN2ALDH1A1
SCHEMBL20829121 0.67 ALDH1A1 (0.59) HPGDKDM4ETSHRMAPTSMN1; SMN2
SCHEMBL4072322 0.66 DNMT1 (0.42) HPGDKDM4ETSHRMAPTSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115107391-B Thermosensitive recording medium, laser printing method and laser printing apparatus 株式会社理光 2024-04-19 CN disclosed
CN-117083182-A Thermosensitive recording layer forming liquid, thermosensitive recording medium, production method thereof, and image recording method 株式会社理光 2023-11-17 CN disclosed
CN-115298039-A Thermosensitive recording medium, method of manufacturing thermosensitive recording medium, and article 株式会社理光 2022-11-04 CN disclosed
CN-115107391-A Thermosensitive recording medium, laser printing method and laser printing apparatus 株式会社理光 2022-09-27 CN disclosed
CN-110709255-B Recording material and compound 日本曹达株式会社 2021-08-06 CN disclosed
CN-110446616-B Thermosensitive recording medium and article 株式会社理光 2021-06-01 CN disclosed
CN-109328143-B Thermosensitive recording medium and article 株式会社理光 2021-03-23 CN disclosed
CN-110709255-A Recording material and compound 日本曹达株式会社 2020-01-17 CN disclosed