Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNMT1 | P26358 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | WDR5 | P61964 | 1/20 | 0.39 |
| ▸ | TDP2 | O95551 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methane SCHEMBL7937870 | 0.77 | DNMT1 (0.39) | DNMT1ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL18045126 | 0.77 | ALDH1A1 (0.40) | DNMT1ALDH1A1MAPTMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL8606301 | 0.76 | DNMT1 (0.41) | DNMT1ALDH1A1MAPTMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL8605086 | 0.76 | DNMT1 (0.41) | DNMT1ALDH1A1MAPTMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL6558603 | 0.75 | DNMT1 (0.40) | DNMT1ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL29241981 | 0.74 | DNMT1 (0.42) | DNMT1ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL18070183 | 0.74 | DNMT1 (0.36) | DNMT1ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL23443980 | 0.73 | PBRM1 (0.36) | ALDH1A1MAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL40599 | 0.72 | GPR3 (0.52) | MEN1KMT2ASLC6A4POLBCYP1A2 | |
| SCHEMBL29641604 | 0.72 | GPR3 (0.52) | MEN1KMT2ASLC6A4POLBCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2006278-B2 | BENZOFLUORENE COMPOUND AND USE THEREOF | TOSOH CORP (JP) | 2016-10-12 | — | — | EP | disclosed |
| US-8993805-B2 | Benzofluorene compound and use thereof | TOSOH CORPORATION (JP) | 2015-03-31 | — | — | US | disclosed |
| EP-2006278-B1 | BENZOFLUORENE COMPOUND AND USE THEREOF | TOSOH CORP (JP) | 2012-12-26 | — | — | EP | disclosed |
| EP-2006278-A9 | BENZOFLUORENE COMPOUND AND USE THEREOF | Tosoh Corporation (JP) | 2009-08-05 | — | — | EP | disclosed |
| US-20090184312-A1 | BENZOFLUORENE COMPOUND AND USE THEREOF | TOSOH CORPORATION (JP) | 2009-07-23 | — | — | US | disclosed |
| EP-2006278-A2 | BENZOFLUORENE COMPOUND AND USE THEREOF | Tosoh Corporation (JP) | 2008-12-24 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090184312-A1 | BENZOFLUORENE COMPOUND AND USE THEREOF | SLC7A1, SLC43A1, SLC7A5 | DNMT1 4199/4885ALDH1A1 1932/4885MAPT 1842/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.