Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHFR | P00374 | 1/20 | 0.54 |
| ▸ | TLR8 | Q9NR97 | 4/20 | 0.42 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | GHSR | Q92847 | 4/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28909381 | 1.00 | DHFR (0.54) | DHFRTLR8TLR7ALDH1A1KCNH2 | |
| SCHEMBL2072604 | 0.81 | HEXA (0.46) | DHFRALDH1A1KDM4E | |
| SCHEMBL8027987 | 0.78 | ALDH1A1 (0.46) | DHFRALDH1A1KCNH2MEN1KMT2A | |
| Octane SCHEMBL11319760 | 0.78 | TSHR (0.50) | DHFRTLR8TLR7ALDH1A1MEN1 | |
| SCHEMBL17545030 | 0.78 | DHFR (0.54) | DHFRTLR8TLR7HPGDGHSR | |
| SCHEMBL15305985 | 0.77 | DHFR (0.47) | DHFRTLR8TLR7 | |
| SCHEMBL3662375 | 0.77 | DHFR (0.45) | DHFRTLR8TLR7ALDH1A1KCNH2 | |
| Water SCHEMBL28123348 | 0.76 | TLR8 (0.49) | DHFRTLR8TLR7 | |
| SCHEMBL6016268 | 0.76 | DHFR (0.53) | DHFRTLR8TLR7ALDH1A1KCNH2 | |
| SCHEMBL379144 | 0.76 | CASP1 (0.65) | DHFRTLR8TLR7ALDH1A1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112513238-A | Stable compositions comprising leuco compounds | 美利肯公司 | 2021-03-16 | — | — | CN | disclosed |