Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | DHFR | P00374 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3265562 | 0.79 | MEN1 (0.39) | ALDH1A1HTR2AKCNH2KDM4EMEN1 | |
| SCHEMBL440580 | 0.77 | TYR (0.37) | ALDH1A1KCNH2RAB9AMEN1KMT2A | |
| SCHEMBL28572772 | 0.75 | ALDH1A1 (0.35) | ALDH1A1DHFRKCNH2KDM4EMEN1 | |
| SCHEMBL113502 | 0.74 | ALDH1A1 (0.46) | ALDH1A1DHFRHTR2AKCNH2KDM4E | |
| SCHEMBL28529359 | 0.72 | LMNA (0.37) | ALDH1A1KCNH2KDM4EMEN1KMT2A | |
| SCHEMBL27705339 | 0.72 | ALDH1A1 (0.36) | ALDH1A1KCNH2MEN1KMT2AHPGD | |
| SCHEMBL29151924 | 0.72 | ALDH1A1 (0.36) | ALDH1A1DHFRHTR2AKCNH2KDM4E | |
| SCHEMBL11116904 | 0.71 | ALDH1A1 (0.42) | ALDH1A1KDM4ERAB9AMAPT | |
| Bromide SCHEMBL25430864 | 0.71 | ALDH1A1 (0.35) | ALDH1A1DHFRHTR2AKCNH2KDM4E | |
| SCHEMBL9626275 | 0.71 | TYMP (0.33) | ALDH1A1KCNH2MEN1KMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0975626-A1 | ENAMINE DERIVATIVES FOR USE AS ANTIOXYDANTS FOR POLYMERS | Great Lakes Chemical (Europe) GmbH (CH) | 2000-02-02 | — | — | EP | claimed |
| WO-1998047893-A1 | ENAMINE DERIVATIVES FOR USE AS ANTIOXYDANTS FOR POLYMERS | GREAT LAKES CHEMICAL (EUROPE) GMBH (CH) | 1998-10-29 | — | — | WO | claimed |