Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 3/20 | 0.42 |
| ▸ | MGLL | Q99685 | 4/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.40 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ABL1 | P00519 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | LIPE | Q05469 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | PTGES | O14684 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28538489 | 0.75 | GAA (0.45) | PTGS1KDM4EGAACYP2D6MAPT | |
| SCHEMBL28527744 | 0.74 | IDH2 (0.40) | NOTUMKDM4EABL1LMNAGAA | |
| SCHEMBL31285854 | 0.73 | L3MBTL1 (0.50) | HSD11B1MGLLLMNAL3MBTL1LIPE | |
| SCHEMBL22605549 | 0.73 | L3MBTL1 (0.50) | HSD11B1MGLLLMNAL3MBTL1LIPE | |
| SCHEMBL3277487 | 0.71 | SCN10A (0.37) | NOTUMKDM4EABL1LMNACYP3A4 | |
| SCHEMBL22605560 | 0.70 | HSD11B1 (0.48) | HSD11B1MGLLPTGS1P2RX1L3MBTL1 | |
| SCHEMBL6575271 | 0.70 | HSD11B1 (0.50) | HSD11B1MGLLKDM4EL3MBTL1GAA | |
| SCHEMBL4148296 | 0.70 | HSD11B1 (0.52) | HSD11B1MGLLKDM4EL3MBTL1RAB9A | |
| SCHEMBL330029 | 0.69 | ALDH1A1 (0.43) | KDM4ELMNAL3MBTL1GAAMAPT | |
| SCHEMBL28521995 | 0.68 | ALDH1A1 (0.39) | KDM4ELMNAL3MBTL1GAACYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111848598-A | Heterocyclic ring-containing compound, application thereof and composition containing heterocyclic ring-containing compound | 健艾仕生物医药有限公司 | 2020-10-30 | — | — | CN | disclosed |