Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.50 |
| ▸ | MGLL | Q99685 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.47 |
| ▸ | CFTR | P13569 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.42 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1341836 | 0.92 | HDAC3 (0.51) | HSD11B1MGLLMAPTGAAALDH1A1 | |
| SCHEMBL8880100 | 0.92 | HSD11B1 (0.48) | HSD11B1MGLLMAPTGAAALDH1A1 | |
| SCHEMBL29990240 | 0.92 | HDAC3 (0.51) | HSD11B1MGLLMAPTGAAALDH1A1 | |
| SCHEMBL3918618 | 0.91 | ALDH1A1 (0.47) | HSD11B1MGLLMAPTGAAALDH1A1 | |
| SCHEMBL3920568 | 0.90 | HDAC3 (0.54) | HSD11B1MGLLMAPTGAAALDH1A1 | |
| SCHEMBL29953271 | 0.90 | HDAC3 (0.54) | HSD11B1MGLLMAPTGAAALDH1A1 | |
| SCHEMBL3908300 | 0.90 | HDAC3 (0.54) | HSD11B1MGLLMAPTGAAALDH1A1 | |
| SCHEMBL5209254 | 0.87 | HTR3E (0.55) | HSD11B1MGLLMAPTGAAALDH1A1 | |
| SCHEMBL3913227 | 0.87 | GLA (0.50) | HSD11B1MGLLMAPTGAAALDH1A1 | |
| Hydrochloric Acid SCHEMBL5212698 | 0.86 | HTR3E (0.54) | HSD11B1MGLLMAPTGAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 92 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0747365-B1 | Process and intermediates for the manufacture of herbicidal 1- [2-(cyclopropylcarbonyl)phenyl] sulfamoyl -3-(4,6-dialkoxy-2-pyrimidinyl)urea compounds | BASF AG (DE) | 2004-08-11 | — | — | EP | claimed |
| EP-0852224-B1 | Aryne intermediates towards the preparation of herbicidal sulfamoyl urea and a process for their preparation | AMERICAN CYANAMID CO (US) | 2001-10-31 | — | — | EP | claimed |
| EP-0849262-B1 | Aminophenyl ketone derivatives and a method for the preparation thereof | AMERICAN CYANAMID CO (US) | 2001-10-17 | — | — | EP | claimed |
| US-6150301-A | Chemical abscission of fruits at low application rates | WILCOX MERRILL (US) | 2000-11-21 | — | — | US | claimed |
| US-6127576-A | Aminophenyl ketone derivatives and a method for the preparation thereof | AMERICAN CYANAMID COMPANY (US) | 2000-10-03 | — | — | US | claimed |
| US-5856576-A | Aryne intermediates and a process for the preparation thereof | AMERICAN CYANAMID COMPANY (US) | 1999-01-05 | — | — | US | claimed |
| EP-0682007-B1 | Method for the preparation of 4-halo-2'-nitrobutyrophenone | AMERICAN CYANAMID CO (US) | 1998-10-07 | — | — | EP | claimed |
| EP-0852224-A1 | Aryne intermediates towards the preparation of herbicidal sulfamoyl urea and a process for their preparation | American Cyanamid Company (US) | 1998-07-08 | — | — | EP | claimed |
| EP-0849262-A1 | Aminophenyl ketone derivatives and a method for the preparation thereof | American Cyanamid Company (US) | 1998-06-24 | — | — | EP | claimed |
| EP-0655436-B1 | Improved process for the manufacture of cycloalkyl and haloalkyl o-aminophenyl ketones | AMERICAN CYANAMID CO (US) | 1998-03-11 | — | — | EP | claimed |
| US-5559234-A | Process for the manufacture of herbicidal 1-{[2-(cyclopropylcarbonyl)phyenyl]sulfamoyl}-3-(4,6-dialkoxy-2-pyrimidinyl)urea compounds | AMERICAN CYANAMID COMPANY (US) | 1996-09-24 | — | — | US | claimed |
| EP-0577945-B1 | Herbicide intermediate o-nitrophenyl cyclopropyl ketone and a method for the preparation thereof | AMERICAN CYANAMID CO (US) | 1996-08-14 | — | — | EP | claimed |
| EP-0682007-A1 | Method for the preparation of 4-halo-2'-nitrobutyrophenone | AMERICAN CYANAMID COMPANY (US) | 1995-11-15 | — | — | EP | claimed |
| EP-0463287-B1 | 1-((O-(cyclopropylcarbonyl)phenyl)sulfamoyl)-3-(4,6-dimethoxy-2-pyrimidinyl)urea and method for the preparation thereof | AMERICAN CYANAMID CO (US) | 1995-09-20 | — | — | EP | claimed |
| EP-0655436-A1 | Improved process for the manufacture of cycloalkyl and haloalkyl o-aminophenyl ketones | AMERICAN CYANAMID COMPANY (US) | 1995-05-31 | — | — | EP | claimed |
| US-5364968-A | Herbicide intermediate o-nitrophenyl cyclopropyl ketone and a method for the preparation thereof | AMERICAN CYANAMID COMPANY (US) | 1994-11-15 | — | — | US | claimed |
| US-5362911-A | Process for the preparation of o-aminophenyl cyclo-propyl ketone | AMERICAN CYANAMID COMPANY (US) | 1994-11-08 | — | — | US | claimed |
| EP-0577945-A1 | Herbicide intermediate o-nitrophenyl cyclopropyl ketone and a method for the preparation thereof | AMERICAN CYANAMID COMPANY (US) | 1994-01-12 | — | — | EP | claimed |
| US-5107023-A | Herbicides | AMERICAN CYANAMID COMPANY (US) | 1992-04-21 | — | — | US | claimed |
| EP-0463287-A1 | 1-((O-(cyclopropylcarbonyl)phenyl)sulfamoyl)-3-(4,6-dimethoxy-2-pyrimidinyl)urea and method for the preparation thereof | AMERICAN CYANAMID COMPANY (US) | 1992-01-02 | — | — | EP | claimed |