Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B3 | P37058 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HTR7 | P34969 | 2/20 | 0.38 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.37 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.36 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.36 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5858271 | 0.79 | P2RX7 (0.45) | HSD17B3LMNAP2RX7KDM4EALDH1A1 | |
| SCHEMBL27792151 | 0.76 | PARP1 (0.46) | LMNAP2RX7KDM4EALDH1A1MEN1 | |
| SCHEMBL5859072 | 0.76 | HTR7 (0.44) | HSD17B3P2RX7KDM4EHTR7GABRA5 | |
| SCHEMBL10842869 | 0.76 | KMT2A (0.51) | HSD17B3LMNAP2RX7ALDH1A1HTR7 | |
| SCHEMBL12092900 | 0.76 | TSHR (0.46) | HSD17B3LMNAP2RX7HTR7GABRA5 | |
| SCHEMBL3829038 | 0.76 | LMNA (0.49) | LMNAALDH1A1RAB9ACYP1A2NPC1 | |
| SCHEMBL21383930 | 0.75 | MTNR1A (0.44) | HSD17B3LMNAP2RX7KDM4EALDH1A1 | |
| SCHEMBL5218001 | 0.75 | HSD17B3 (0.43) | HSD17B3LMNAP2RX7HTR7GABRA5 | |
| SCHEMBL5218004 | 0.75 | HSD17B3 (0.43) | HSD17B3LMNAP2RX7KDM4EALDH1A1 | |
| SCHEMBL12093742 | 0.74 | GRM5 (0.48) | HSD17B3LMNAALDH1A1HTR7GABRA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112236161-A | Modulators of G protein-coupled receptors | 卡莫特治疗学股份有限公司 | 2021-01-15 | — | — | CN | disclosed |