Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LRRK2 | Q5S007 | 10/20 | 0.48 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 4/20 | 0.35 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.34 |
| ▸ | PPARD | Q03181 | 1/20 | 0.34 |
| ▸ | PPARA | Q07869 | 1/20 | 0.34 |
| ▸ | DPP4 | P27487 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 3/20 | 0.34 |
| ▸ | DRD3 | P35462 | 3/20 | 0.34 |
| ▸ | PNMT | P11086 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL227332 | 0.80 | SLC6A4 (0.41) | — | |
| SCHEMBL23783096 | 0.77 | LRRK2 (0.31) | LRRK2 | |
| SCHEMBL22056586 | 0.76 | IDO1 (0.53) | CYP11B2 | |
| SCHEMBL9280511 | 0.75 | DRD2 (0.37) | DRD2 | |
| SCHEMBL25621 | 0.74 | ALDH1A1 (0.32) | — | |
| SCHEMBL14896516 | 0.74 | CA12 (0.35) | — | |
| SCHEMBL25622 | 0.74 | ALDH1A1 (0.32) | — | |
| SCHEMBL7197862 | 0.74 | IDO1 (0.31) | — | |
| SCHEMBL20706314 | 0.73 | LRRK2 (0.44) | LRRK2AKR1C3CYP11B2CYP11B1PPARD | |
| SCHEMBL29944707 | 0.73 | S1PR1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220112185-A1 | NOVEL PHENYL PROPIONIC ACID DERIVATIVES AND USES THEREOF | ILDONG PHARMACEUTICAL CO., LTD. (KR) | 2022-04-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220112185-A1 | NOVEL PHENYL PROPIONIC ACID DERIVATIVES AND USES THEREOF | GPR119, GPR55, GPR65 | LRRK2 3553/4885AKR1C3 603/4885CYP11B2 539/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.