Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMPRSS4 | Q9NRS4 | 1/20 | 0.57 |
| ▸ | MALT1 | Q9UDY8 | 17/20 | 0.54 |
| ▸ | KDR | P35968 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2854162 | 0.89 | NPC1 (0.58) | MALT1 | |
| SCHEMBL2857034 | 0.84 | KDM4E (0.62) | — | |
| SCHEMBL2854798 | 0.84 | MEN1 (0.47) | TMPRSS4MALT1KDR | |
| SCHEMBL2850282 | 0.81 | KDM4E (0.58) | — | |
| SCHEMBL2855512 | 0.79 | MALT1 (0.55) | MALT1 | |
| SCHEMBL13513708 | 0.79 | KDM4E (0.53) | MALT1 | |
| SCHEMBL2852818 | 0.79 | NPC1 (0.50) | MALT1 | |
| SCHEMBL2856075 | 0.79 | NAMPT (0.56) | MALT1 | |
| SCHEMBL2860841 | 0.78 | DHODH (0.55) | — | |
| SCHEMBL2850859 | 0.78 | KEAP1 (0.51) | MALT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | disclosed |