Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | CNR2 | P34972 | 4/20 | 0.46 |
| ▸ | CNR1 | P21554 | 3/20 | 0.46 |
| ▸ | TMPRSS4 | Q9NRS4 | 1/20 | 0.45 |
| ▸ | KDR | P35968 | 5/20 | 0.42 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.42 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2852636 | 0.89 | NPC1 (0.46) | MEN1POLBKMT2ATRPV1NOTUM | |
| SCHEMBL2848317 | 0.85 | MAPT (0.46) | MEN1POLBKMT2AKDM4ENPC1 | |
| SCHEMBL2852244 | 0.84 | MAPT (0.48) | MEN1POLBKMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL2852783 | 0.84 | TMPRSS4 (0.57) | TMPRSS4KDRMALT1 | |
| SCHEMBL2860975 | 0.83 | MAPT (0.49) | MEN1POLBKMT2AKDRKDM4E | |
| SCHEMBL2850258 | 0.82 | MAPT (0.51) | MEN1KMT2AKDM4ESMN1; SMN2HPGD | |
| SCHEMBL2861576 | 0.82 | MAPT (0.45) | POLBCNR1KDM4ENPC1SMN1; SMN2 | |
| SCHEMBL2854221 | 0.81 | MAPT (0.51) | MEN1KMT2ACNR2TMPRSS4KDM4E | |
| SCHEMBL2854572 | 0.81 | RAB9A (0.44) | MEN1KMT2AKDM4ENPC1RAB9A | |
| SCHEMBL2852565 | 0.81 | MAPT (0.42) | MEN1KMT2ACNR1KDM4ENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |