Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 8/20 | 0.57 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.51 |
| ▸ | TRPC3 | Q13507 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | CNR2 | P34972 | 1/20 | 0.45 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.45 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.45 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.45 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.45 |
| ▸ | DDR2 | Q16832 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2859678 | 0.91 | CCR1 (0.55) | CCR1DGAT2TRPC3MAPTALDH1A1 | |
| SCHEMBL2858191 | 0.91 | CCR1 (0.56) | CCR1DGAT2TRPC3KDM4EALDH1A1 | |
| SCHEMBL2855565 | 0.86 | CCR1 (0.66) | CCR1TRPC3MAPTKDM4EALDH1A1 | |
| SCHEMBL2855701 | 0.85 | CCR1 (0.54) | CCR1DGAT2TRPC3KDM4EALDH1A1 | |
| SCHEMBL2855705 | 0.85 | CCR1 (0.56) | CCR1DGAT2TRPC3KDM4EALDH1A1 | |
| SCHEMBL2855623 | 0.85 | CCR1 (0.44) | CCR1DGAT2MAPTNPC1LMNA | |
| SCHEMBL2852015 | 0.83 | CCR1 (0.63) | CCR1TRPC3MAPTKDM4EALDH1A1 | |
| SCHEMBL2854425 | 0.83 | CCR1 (0.60) | CCR1TRPC3MAPTKDM4EALDH1A1 | |
| SCHEMBL2850316 | 0.83 | TP53 (0.59) | CCR1DGAT2MAPTKDM4EALDH1A1 | |
| SCHEMBL2856127 | 0.83 | CCR1 (0.64) | CCR1DGAT2MAPTTP53KLKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | disclosed |