Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 9/20 | 0.70 |
| ▸ | HTT | P42858 | 6/20 | 0.70 |
| ▸ | LMNA | P02545 | 5/20 | 0.64 |
| ▸ | CNR2 | P34972 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | HTR6 | P50406 | 1/20 | 0.52 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8685734 | 0.83 | ALDH1A1 (0.49) | ALDH1A1SMN1; SMN2HTTLMNACNR2 | |
| SCHEMBL6705979 | 0.82 | SMN1; SMN2 (0.72) | ALDH1A1SMN1; SMN2HTTLMNATDP1 | |
| SCHEMBL6802019 | 0.82 | ALDH1A1 (0.70) | ALDH1A1SMN1; SMN2HTTLMNATDP1 | |
| SCHEMBL28467331 | 0.82 | ALDH1A1 (0.70) | ALDH1A1SMN1; SMN2HTTLMNATDP1 | |
| SCHEMBL30487286 | 0.82 | ALDH1A1 (1.00) | ALDH1A1SMN1; SMN2HTTLMNATDP1 | |
| SCHEMBL30487282 | 0.82 | SMN1; SMN2 (0.72) | ALDH1A1SMN1; SMN2HTTLMNATDP1 | |
| SCHEMBL4357272 | 0.82 | ALDH1A1 (1.00) | ALDH1A1SMN1; SMN2HTTLMNATDP1 | |
| SCHEMBL28533308 | 0.82 | POLB (0.59) | ALDH1A1SMN1; SMN2HTTLMNATDP1 | |
| SCHEMBL4363865 | 0.79 | ALDH1A1 (0.74) | ALDH1A1SMN1; SMN2HTTLMNATDP1 | |
| SCHEMBL8690882 | 0.79 | TDP1 (0.65) | ALDH1A1SMN1; SMN2HTTLMNATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108358923-B | Sophoridine pyrrole and indole derivatives, and preparation method and application thereof | 广西大学 | 2020-11-03 | — | — | CN | claimed |
| CN-108358923-A | Sophoridine pyrroles, indole derivatives and the preparation method and application thereof | 广西大学 | 2018-08-03 | — | — | CN | claimed |